Figure 3From: Prospective malaria control using entomopathogenic fungi: comparative evaluation of impact on transmission and selection for resistanceComparison of virulence characteristics and fitness costs associated with given reductions in EIR. Top panels show different combinations of values for initiation day (x-axis) and daily mortality rate (y-axis) which achieve the denoted reductions in EIR (RAIB). The mortality rate required to achieve a given RAIB increases for later initiation days, up to an initiation day beyond which the target RAIB cannot be achieved, at which point the plots stop. With 50% biopesticide coverage, no virulence parameter combinations achieve 99% RAIB. Bottom panels show the selection coefficients corresponding to the same set of virulence parameter values, eg, the 99% RAIB value plotted for initiation day 2 gives the fitness cost for susceptibility to a biopesticide with initiation day 2 combined with the mortality rate required to achieve a 99% RAIB. Higher selection coefficients indicate stronger selection pressure for resistance.Back to article page