| Non-pregnant women | Pregnant women | P-value |
---|---|---|---|
 | Median (Range) | Median (Range) |  |
Number of patients | 12 | 12 | - |
Daily piperaquine (phosphate) dose (mg/kg) | 18.1 (15.1-24.2) | 17.6 (13.6-21.7) | 0.884 |
Daily piperaquine (base) dose (mg/kg) | 10.5 (8.71-13.9) | 10.2 (7.83-12.5) | 0.884 |
Age (years) | 21.0 (16.0-43.0) | 26.0 (18.0-33.0) | 0.977 |
Body weight (kg) | 53.0 (44.0-81.0) | 59.0 (50.0-72.0) | 0.544 |
Height (cm) | 163 (150–174) | 166 (150–174) | 0.908 |
Estimated gestational age (weeks) | - | 32.0 (15.3–40.1) | - |
Parasitemia (parasites/μL) | 13200 (936–68700) | 12900 (624–118000) | 0.488 |
Days of fever | 2.5 (1–6) | 3 (1–6) | 0.095 |
Fever (°C) | 38.3 (36.7-40.0) | 38.2 (36.6-39.9) | 0.795 |
Haemoglobin (g/dL) | 8.70 (7.60-11.5) | 9.65 (8.00-12.0) | 0.099 |
Urea (mg/dL) | 26.0 (24.0-28.0) | 25.0 (24.0-28.0) | 0.036 |
Serum glutamic pyruvic transaminase (IU/L) | 5.00 (2.00-10.0) | 4.50 (2.00-9.00) | 0.445 |
Serum glutamic oxaloacetic transaminase (IU/L) | 13.5 (2.00-18.0) | 13.0 (3.00-21.0) | 0.727 |