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Table 2 Structured population association test between malaria and control samples

From: IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil

Gene

SNP

dbSNP ID

Allele

Frequency (%)

PQui2

PStrat

    

Control

Malaria

  

IL1B

−5839C > T

rs1143629

C

46.2

54.4

0.01

0.04

IL4R

1902A > G

rs1801275

A

32.5

38.7

0.04

0.02

IL6

−174C > G

rs1800795

C

20.9

17.8

0.25

0.50

IL10

−592A > C

rs1800872

A

34.2

37.7

0.27

0.40

IL12B

458A > G

rs2546890

A

40.1

33.6

0.04

0.12

IL12RB1

−1094A > G

rs375947

G

23.4

20.9

0.36

0.19

 

−641C > T

rs11575934

G

20.8

19.9

0.72

0.79

SP110

14622C > T

rs2114592

T

8.2

9.3

0.55

0.75

TNF

−1031C > T

rs1799964

C

24.0

21.9

0.44

0.10

 

−238A > G

rs361525

A

7.4

6.1

0.44

0.37

 

−857C > T

rs1799724

T

14.4

15.0

0.79

0.12

IFNG

874A > T

rs2430561

A

25.8

28.3

0.38

0.29

IFNGR1

−56 T > C

rs2234711

C

39.8

38.1

0.59

0.71