Drug | Subjects | Median age (range) [years] | No. of patients | Duration of sampling | CL[L/h] | V SS [L] | Ref. |
---|---|---|---|---|---|---|---|
AM | Patients | 10 (1–78) | 135 | 7 days | 598 | 129 | Present study |
 | Patients | 22 (14–60) | 217 | 360 h | 252a | 304a | [47] |
 | Patients | 4.0 (1–10) | 50 | 72 h | 182–700b | 364 | [46] |
 | Patients | 7.7 ± 1.4c | 13 | 28 days | 102 | 1263 | [48] |
 | Pregnant women | 21 (16–35) | 21 | 10 h | 1054d | 2602d | [49] |
DHAe | Patients | 10 (1–78) | 135 | 7 days | 419 | 129f | Present study |
 | Patients | 22 (14–60) | 217 | 360 h | 237a | 147a | [47] |
 | Pregnant women | 21 (16–35) | 21 | 10 h | 564 | 69 | [49] |
LF | Patients | 9 (1–78) | 143 | 7 days | 7.7 | 265f | Present study |
 | Patients | 22 (14–60) | 217 | – | 21 | 301 | [47] |
 | Patients | 23 (13–59) | 102 | – | 7 | 298 | [32] |
 | Patients | 20 (5–66) | 309 | – | 7.6 | 361 | [32] |
 | Pregnant women | 24 (15–42) | 103 | 336 h | 8.7 | 257 | [50] |
 | Patients | 4.0 (1–10) | 50 | 72 h | 5.4 | 623 | [46] |
 | Patients | 7.7 ± 1.4c | 13 | 28 days | 7.29 | 506 | [48] |
DLFg | Patients | 9 (1–78) | 143 | 7 days | 336 | 265f | Present study |
 | Patients | 7.7 ± 1.4c | 13 | 28 days | 701 | 119’500 | [48] |
MQ | Patients | 18 (2–57) | 63 | 14 days | 2.4 | 625 | Present study |
 | Patients | 14.8 (8–61) | 128 | 28 days | 1.4 | 574.7 | [8] |
 | Patients | 9.3 (4–15) | 74 | 28 days | 3.71 | 1,089.2 | [8] |
 | Prophylaxis | 26h (18–55) | 1,111 | 26 weeks | 1.75 | 863 | [51] |
 | Patients | 19 (2–55) | 50 | 63 days | 2.1 | 767.62 | [52] |
PPQ | Patients | 18 (7–53) | 60 | 14 days | 109 | 42,820 | Present study |
 | Patients | 3–55 | 98 | 63 days | 98h | 61,180i | [53] |
 | Patients | 6 (2–10) | 236 | 42 days | 29 | 14,972 | [54] |
 | Pregnant women | 25 (18–43) | 24 | 84 days | 90 | 37,030 | [55] |
 | Non-pregnant women | 27.5 (18–45) | 24 | 84 days | 92 | 58,030 | [55] |