Figure 4

Phylogenetic tree of P. vivax and P. cynomolgi MSP-3α sequences. Trees constructed from Neighbor-joining (A) and Bayesian methods (B) are shown with nodes with greater than 50% bootstrap or 0.50 posterior probability support, respectively, noted. Sequences are labelled by species (Pv or Pc), country of isolate origin, and PCR-RFLP haplotype. Curved, gray lines connect recombination events between P. vivax sequences as detected by the RDP [53] algorithm.