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Table 6 Performance results for a putative qualitative diagnostic test modeled against the quantitative results described in Table 3

From: G6PD testing in support of treatment and elimination of malaria: recommendations for evaluation of G6PD tests

 

10% cut-off

20% cut-off

30% cut-off

60% cut-off

Cutoff value (U/g Hb)

1.07

2.14

3.21

6.42

Number of samples with G6PD levels less than cut-off (percentage)

14 (2.8)

24 (4.8)

28 (5.6)

41 (8.2)

Sensitivity percentage (95% CI)

100

95.8

89.3

68.3

(73–100)

(77–100)

(71–97)

(52–81)

Specificity percentage (95% CI)

97.1

98.9

99.4

100

(95–98)

(97–100)

(98–100)

(99–100)

Positive predictive value percentage (95% CI)

0.5

0.82

0.89

1.00

(0.31-0.69)

(0.62-0.93)

(0.71-0.97)

(0.84-1.00)

Negative predictive value percentage (95% CI)

1.00

1.00

0.99

0.97

(0.99-1.00)

(0.99-1.00)

(0.98-1.00)

(0.95-0.98)

  1. CI: confidence interval; Hb: haemoglobin; U: International Unit.