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Figure 3 | Malaria Journal

Figure 3

From: Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development

Figure 3

Multiple sequence alignment of the catalytic subdomain IIa. Plasmodium falciparum (FCR-3) calpain (GenBank, ADQ00190.1), P. falciparum (3D7) calpain (GenBank, ABR187921.1), Plasmodium vivax calpain (GenBank, EDL46679.1), and Homo sapiens calpain-7 (GenBank, NP_055111) were aligned using Crystal W2 program. P. falciparum (FCR-3) calpain was 33.6% identical to H. sapiens calpain-7 and 73.5% identical to P. vivax calpain. The predicted histidine (His 1179) and asparagine (Asn 1195) residues were shown in red with cysteine (Cys 1035).

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Malaria Journal

ISSN: 1475-2875

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