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Figure 2 | Malaria Journal

Figure 2

From: Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids

Figure 2

In vivo ED50 of hybrids 1 – 3 and artesunate. The in vivo ED50 of hybrid 1 (A), hybrid 2 (B), hybrid 3 (C) and artesunate (D) was determined. Plasmodium vinckei-infected mice were treated once daily by ip (white squares) or po (black squares) injections for 4 consecutive days. Parasitaemia was monitored at day 5 and expressed as a percentage of the control. Results are the mean of at least 3 mice per dosage ± SD.

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Malaria Journal

ISSN: 1475-2875

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