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Figure 5 | Malaria Journal

Figure 5

From: Characterization of the Anopheles gambiae octopamine receptor and discovery of potential agonists and antagonists using a combined computational-experimental approach

Figure 5

Pharmacological characterization of AgOAR45B mutants. A. Dose response curves of optopamine E161Q (closed triangles), E161A (open triangles), D100N (closed squares), D100A (open squares), D100N/E161Q (closed diamonds), and D100A/E161A (open diamonds) double mutants. B. Dose response curves of optopamine S206A (closed boxes), S210A (closed triangles) and S206A/S210A double mutants (open circles). The same control wild-type AgOAR45B (closed circles) data is presented in both A and B. Data are expressed as % 1 μM octopamine response. Means ± SD of three independent experiments are presented.

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Malaria Journal

ISSN: 1475-2875

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