Figure 3

P. yoelii 17XL upregulates RANTES, CCR1, CCR3 and CCR5 mRNA expression in mouse brain. Semi-quantitative RT-PCR comparative analysis of RANTES CCR1, CCR3 and CCR5 mRNA expressions in brains of P. yoelii 17XL-infected (I, black bars) days two, four, six, and eight post-infections and control (C, grey bars) mice. Densitometric data presented were log-transformed (to adjust for small sample size) and represent the mean and ± SEM of infected (n = 5) and control (n = 5) cases, normalized to those for GAPDH. Asterisk(s) indicate statistically significant differences between P. yoelii 17XL infected and control groups.