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Table 3 Statistical comparison of the efficacy of the four different antimalarial drug combinations.

From: Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal

 

Artesunate-amodiaquine

Artesunate-mefloquine

Artemether-lumefantrine (four doses)

Artemether-lumefantrine (six doses)

Amodiaquine-sulphadoxine-pyrimethamine

Overall efficacy

97.5%

97.9%

82.8%

100%

98.8%

Artesunate-amodiaquine

0

NS

P < 0.001

NS

NS

Artesunate-mefloquine

 

0

p < 0.001

NS

NS

Artemether-lumefantrine (four doses)

  

0

p < 0.001

p = 0.001

Artemether-lumefantrine (six doses)

   

0

NS

Amodiaquine-sulphadoxine-pyrimethamine

    

0

  1. NS: not significant.