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Table 3 Prevalence and levels of antibodies to the OR domain of the P. falciparum P126 protein in Candeias do Jamari and Peixoto de Azevedo groups regardless of the infection patterns.

From: Evaluation of the genetic polymorphism of Plasmodium falciparum P126 protein (SERA or SERP) and its influence on naturally acquired specific antibody responses in malaria-infected individuals living in the Brazilian Amazon

 

PA (a)

CJ-1993 (b)

CJ-2002 (c)

P values

IgG

71/90 (79%)

53/76 (70%)

58/78 (74%)

n.s.

 

4.5 ± 2.8

4.9 ± 3.0

8.6 ± 8.3

a × c: 0.0006; b × c: 0.002

IgM

49/90 (54%)

43/68 (63%)

63/78 (81%)

a × c: 0.0006; b × c: 0.02

 

2.3 ± 1.5

3.4 ± 2.0

4.9 ± 4.8

a × c: 0.0002; b × c: 0.04

IgG1

45/70 (64%)

43/49 (87%)

14/58 (24%)

a × b: 0.007; a × c: < 0.0001; b × c: < 0.0001

 

2.3 ± 2.0

3.2 ± 2.0

1.9 ± 0.7

b × c: 0.001

IgG2

5/70 (7%)

7/49 (14%)

21/58 (36%)

a × c: 0.0001; b × c: 0.01

 

1.3 ± 0.4

2.8 ± 2.8

1.3 ± 0.4

n.s.

IgG3

68/70 (97%)

47/49 (96%)

35/58 (60%)

a × c: < 0.0001; b × c: < 0.0001

 

8.1 ± 6.4

10.2 ± 9.7

7.9 ± 6.1

n.s.

IgG4

30/70 (43%)

23/49 (47%)

24/58 (41%)

n.s.

 

1.3 ± 0.2

1.6 ± 0.7

2.5 ± 2.2

n.s.

  1. The data represent the number of responders/number of tested individuals (the percentage of responders is given in parentheses) and the antibody levels expressed as mean of OD index ± SD. The Student's t-test was used to analyse the differences in mean values, the Chi-square test was used to analyse the difference in prevalence of positive responses.