Figure 3
From: Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase
5' repeat motif, upstream flanking region, dhfr genotype and downstream flanking region of selected isolates. Numbers in columns 2 through 9 indicate the number of repeats of a given type, with the first repeat beginning 2,608 bp upstream of dhfr per the reference sequence. Colours in the dhfr genotype column reflect dhfr genotype, as in Figure 3. Colours upstream and downstream of dhfr reflect similarity of flanking regions. The 5' indel and in-frame indel within dhfr are coded as in Figure 3. All isolates bear the 174G mutation in codon 58.