Table 4 Performance characteristics of Hexagon Malaria Combi™ rapid test at different parasite densities in detecting the different Plasmodium species.
Parasite density | Sensitivity % (95%CI) | Specificity % (95%CI) | Accuracy % | Reliability |
|---|---|---|---|---|
P. falciparum only | ||||
<500 | 50 (33.4–66.6) | 83 (52–98) | 66.6 | 0.6 |
501–5,000 | 76.9 (62.9–90.9) | 87 (60–98) | 97.5 | 0.8 |
>5,000 | 100 (99.7–100) | 92 (82–97) | 98 | 0.8 |
Total | 87.50 (76.5–98.5) | 98 (93–100) | 95.6 | 0.8 |
Non-falciparum species | ||||
<500 | 0 (0–94.5) | 67 (43–85) | 98 | 0.7 |
501–5,000 | 66.7 (34–99.3) | 88(47–100) | 93 | 0.7 |
>5,000 | 100 (99.7–100) | 98.(89–100) | 96.5 | 0.7 |
Total | 80 (52.3–99.6) | 92 (83–97) | 94 | 0.8 |
Mixed infections with Plasmodium falciparum (Plasmodium vivax not included) | ||||
<500 | 50 (28.6–71.4) | 62 (46–75) | 95.5 | 0.7 |
501–5,000 | 66.7 (46.51–86.8) | 66(53–78) | 92 | 0.7 |
>5,000 | 94.1 (46.51–99.9) | 92 (82–97) | 93.1 | 0.8 |
Total | 84 (68.3–99.7) | 95 (74–100) | 89.5 | 0.8 |