Figure 1From: How antimalarial drug resistance affects post-treatment prophylaxisIn this diagram a slowly eliminated drug given over three days has a single component (monoexponential) elimination phase with a half-life of 5.5 days. This corresponds with a one-compartment model. The vertical axis has a logarithmic scale. The in-vivo MIC is 1.25 μmol/L. Each doubling of MIC shortens the PTP by one half-life.Back to article page