Table 1 A summary of selected features calculated for annotated proteins in Plasmodium falciparum (a total of 5,411 proteins were analysed).
Feature | Occurrence |
|---|---|
BLAST vs. PDB hits with at least 25% identity | 27% |
Hits vs. Pfam with E-value < 1 × 10-15 | 32% |
No Pfam hits | 43% |
Threading Z score > 3.95 | 8% |
One or more predicted coiled-coil regions | 10% |
Predicted to be transported out of the RBC (Pexel) | 5% |
Predicted to contain at least one transmembrane helix | 30% |
Predicted small molecule binding by SMID | 22% |
Protein-protein interaction by yeast-two hybrid results | 15% |
Predicted ≤ 40% disorder or no regular secondary structure | 60% |
Mean percentage low complexity per sequence | 16% |