Table 1 Baseline characteristics of patients receiving fixed or loose artesunate and amodiaquine

Male: n (%)*

193 (51.5)

212 (56.5)

0.16

Age (months): Mean (SD)

27.5 (14.2)

27.5 (15.2)

0.78

< 12 m

n = 54

n = 59

1–5 y

n = 321

n = 316

Weight (kg): Mean (SD)

10.5 (3.0) n = 373

10.4 (3.1)

0.66

Temp (°C): Mean (SD)

38.4 (0.8)

38.4 (0.9)

0.52

Splenomegaly: n (%)

37 (9.9)

38 (10.1)

0.90

Parasite count (/μL): Median (range)

14.5 (1 – 516.6)

14.2 (1 – 410)

0.78

Haemoglobin (g/dL): Mean (SD)

8.3 (1.7) n = 374

8.2 (1.7) n = 371

0.50

Total WCC (10^9/L): Mean (SD)

11.5 (5.1) n = 337

11.6 (4.8) n = 337

0.42

Platelet count (10^9/L): Mean (SD)

174.4 (112.6) n = 337

183.9 (113.4) n = 338

0.20

AST (IU/L): Mean (SD)

71.0 (71.1) n = 303

70.0 (76.3) n = 298

0.53

ALT (IU/L): Mean (SD)

31.8 (44.9) n = 299

32.0 (53.1) n = 293

0.87

Total bilirubin (μmol/L): Mean (SD)

26.0 (27.8) n = 321

25.7 (33.9) n = 311

0.77