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Figure 6 | Malaria Journal

Figure 6

From: Structural insights into chondroitin sulphate A binding Duffy-binding-like domains from Plasmodium falciparum: implications for intervention strategies against placental malaria

Figure 6

Comparison of sulphate binding site in all the CSA-binding var2CSA DBL domains. (a) Superposition of all CSA-binding DBL domains onto the A4 DBL 3X crystal structure (PDB code: 3BQK). The sulphate-binding site is highlighted. (b) Close view of the sulphate-binding site. The loop region bearing the important Gly and Lys residues is magnified. This loop is either absent or is in a different orientation in all CSA-binding domains except A4 (magenta) and 3D7 (green) DBL 3X.

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Malaria Journal

ISSN: 1475-2875

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