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Table 10 Reproducibility of the CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test: HRP-2 line intensities

From: Evaluation of a rapid diagnostic test (CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test) for the diagnosis of malaria in a reference setting

 

Readings HRP-2 line Observer

Species and parasite density

Observer 1

Observer 2

Observer 3

P. falciparum

   

85 asexual parasites/μl

S S S S S

S S S S S

S S S S S

90 asexual parasites/μl

M M M M M

M W M M W

M M M M M

180 asexual parasites/μl

N N F N N

N N F N N

N N N N N

200 asexual parasites/μl

M M M M M

W M W M W

W M M M M

244 asexual parasites/μl

M M M M M

M M M W M

M M M M M

465 asexual parasites/μl

M M S M M

M M S M M

M S S S S

720 asexual parasites/μl

S M S S S

M M M S S

S M S S S

4,464 asexual parasites/μl

M M M M M

M M M M M

S M M S S

1,000,000 asexual parasites/μl

W W W M W

W W W W F

W W W W W

P. malariae

   

275 asexual parasites/μl

N F N N N

N F N N N

N F N N N

1,215 asexual parasites/μl

N N N N N

N N N N N

N N N N N

P. ovale

   

468 asexual parasites/μl

N N N N N

N N N N N

N N N N N

1,100 asexual parasites/μl

N N N N N

N N N N N

N N N N N

P. vivax

   

432 asexual parasites/μl

N N N N N

N N N N N

N N N N N

846 asexual parasites/μl

N N N N N

N N N N N

N N N N N

  1. HRP-2 line intensity of the test performed on five consecutive moments.
  2. Each character represents a distinct test. N = None, F = Faint, W = Weak, M = Medium, S = Strong