Figure 2From: Drug coverage in treatment of malaria and the consequences for resistance evolution - evidence from the use of sulphadoxine/pyrimethamineAllele frequency changes at dhfr in Rufiji (A), and Kilombero/Ulanga (B). The sensitive allele (dotted line with diamond), the triple mutant N51I + C59R + S108N allele (solid line with squares), and double mutant C59R + S108N (dash-dot line with triangles), double mutant N51I + S108N(dashed line with X).Back to article page