Malaria Journal

Table 1 Prevalence of mutant alleles of pfdhfr and pfdhps in P. falciparum isolates from Hadhramout, Yemen

From: Frequencies distribution of dihydrofolate reductase and dihydropteroate synthetase mutant alleles associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum population from Hadhramout Governorate, Yemen

Mutant alleles^a	Prevalence, n (%)		Total n = 128	P value
Mutant alleles^a	Hajer n = 26	Al-Raydah-Qusyer n = 102	Total n = 128	P value
Pfdhfr
51I	19 (73.1)	88 (86.3)	107 (84)	0.105
59R	0 (00)	1 (1.0)	1 (0.8)	0.797^b
108N	19 (73.1)	88 (86.3)	107 (84)	0.105
164L	0 (00)	0 (00)	0 (00)	NA

Mutant alleles^a	Prevalence, n (%)		Total n = 114	P value
Mutant alleles^a	Hajer n = 25	Al-Raydah-Qusyer n = 89	Total n = 114	P value
Pfdhps
436A	0 (00)	0 (00)	0 (00)	NA
437G	9 (36)	42 (47)	51 (44.7)	0.56
540E	0 (00)	0 (00)	0 (00)	NA

n sample size, NA not applicable
^aMutant alleles are bold and underlined
^bThe difference was examined using Fisher exact test

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ISSN: 1475-2875

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