| Frequency | ALL | SMA | CM | ||||
---|---|---|---|---|---|---|---|---|
Control | Case (SMA, CM) | OR (95Â % CI) | P value | OR (95Â % CI) | P value | OR (95Â % CI) | P value | |
N = 3836 | N = 2379 (556, 890) | |||||||
HbS | 0.072 | 0.013 (0.010, 0.007) | 0.16 (0.12–0.21) | 1.1e−38 | 0.16 (0.09–0.29) | 2.9e−09 | 0.11 (0.06–0.19) | 8.0e−15 |
A968G | 0.066 | 0.054 (0.077, 0.048) | 0.84 (0.74–0.96) | 0.0102 | 1.09 (0.88–1.35) | 0.4212 | 0.73 (0.58–0.91) | 0.0060 |
T542A | 0.012 | 0.007 (0.014, 0.005) | 0.74 (0.53–1.03) | 0.0706 | 1.36 (0.87–2.11) | 0.1727 | 0.47 (0.23–0.99) | 0.0483 |
C202T | 0.032 | 0.023 (0.031, 0.021) | 0.85 (0.70–1.03) | 0.0906 | 1.09 (0.79–1.49) | 0.6065 | 0.82 (0.60–1.11) | 0.1970 |
G6PD_trait | 0.113 | 0.085 (0.130, 0.078) | 0.83 (0.75–0.92) | 0.0006 | 1.14 (0.96–1.36) | 0.1401 | 0.73 (0.61–0.87) | 0.0005 |
G6PD_trait (full) | 0.063 | 0.050 (0.084, 0.047) | 0.80 (0.63–1.01) | 0.0661 | 1.43 (0.99–2.08) | 0.0557 | 0.68 (0.46–1.00) | 0.0524 |