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Table 3 Bi- and multivariate analyses of risk factors for developing a clinical malaria episode, including bed net use and IRS (134 cases, 749 controls, 4 communes)

From: Effectiveness of malaria control interventions in Madagascar: a nationwide case–control survey

Variable

Category

N cases (%)

N controls (%)

Bivariate

Multivariate

Crude OR [95 %CI]

p

Adjusted OR [95 %CI]

p

Every night bed net use and/or IRS the previous year

LLIN use and IRS

28 (16.2)

335 (36.6)

0.28 [0.10–0.78]

0.015

0.28 [0.11–0.72]

0.008

No LLIN use and IRS

60 (34.7)

317 (34.6)

0.43 [0.25–0.74]

0.003

0.44 [0.26–0.74]

0.002

LLIN use and no IRS

12 (6.9)

97 (10.6)

0.34 [0.10–1.11]

0.073

0.37 [0.11–1.25]

0.110

NIBN use and no IRS

6 (3.5)

18 (2.0)

1.00 [0.78–1.30]

0.972

0.90 [0.75–1.09]

0.287

No bed net use and no IRS

67 (38.7)

149 (16.3)

1.00

 

1.00

 

Age group

0–1 year

19 (11.0)

31 (3.4)

5.69 [3.35–9.69]

<0.001

4.78 [2.56–8.92]

<0.001

2–4 years

33 (19.1)

96 (10.5)

3.12 [2.33–4.18]

<0.001

3.02 [1.96–4.65]

<0.001

5–9 years

38 (22.0)

152 (16.6)

2.49 [1.95–3.19]

<0.001

2.38 [1.81–3.12]

<0.001

10–15 years

23 (13.3)

148 (16.2)

1.36 [0.83–2.23]

0.218

1.27 [0.70–2.31]

0.440

15–19 years

24 (13.9)

111 (12.1)

2.17 [1.52–3.09]

<0.001

1.97 [1.48–2.62]

<0.001

≥20 years

36 (20.8)

378 (41.3)

1.00

 

1.00

 

Sex

Male

94 (54.3)

386 (42.1)

1.00

 

1.00

 

Female

79 (45.7)

530 (57.9)

0.59 [0.54–0.66]

<0.001

0.68 [0.56–0.83]

<0.001

Transmission pattern

Fringe

55 (31.8)

219 (23.9)

1.00

 

1.00

 

West

118 (68.2)

697 (76.1)

0.61 [0.25–1.47]

0.268

1.14 [0.94–1.38]

0.196