Fig. 3From: Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trialSummary of TQ-related components detected in incubations of TQ with recombinant human CYP Supersomes. TQ-related compounds detected in 5 and 10 μM incubations of TQ with recombinant human CYP enzymes (Supersomes™), hepatocytes and appropriate controls (retention time and protonated molecular ion observed by UPLC-MS in parenthesis). The Carboxy-TQ derivative observed after prolonged incubation is circled Back to article page