Fig. 3
Retention of hypoxia-exposed Plasmodium falciparum (FUP line)-infected RBCs. a Mean retention rates (± SEM) of ring-infected HbAA (n = 2) and HbAS (n = 2) RBCs in two isolated human spleens over 60 min of perfusion ex vivo. b Mean retention rates (± SEM) of ring-infected HbAA (n = 3), HbAS (n = 5) and HbSS (n = 4) RBCs in microsphilters after exposure to ‘stringent’ hypoxia (0.5 % O2, 5 % CO2, 94.5 % N2) for 15 min. c Mean retention rates (± SEM) of ring-infected HbAA (n = 3), HbAS (n = 5) and HbSS (n = 3) RBCs in microsphilters after exposure to stringent hypoxia for 45 min. d Mean retention rate (± SEM) of mature P. falciparum-infected HbAA (n = 4) and HbAS (n = 5) RBCs in microsphilters