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Fig. 9 | Malaria Journal

Fig. 9

From: Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

Fig. 9

Population-level allele frequency of venous blood (VB) and DBS (sWGA) samples are strongly correlated. Using variant calls from the 1.2 million high quality-biallelic SNP positons, non-reference allele frequencies (NRAF) were compared from matching VB and DBS samples, and a strong correlation between the two sample sets was obtained. Coloured dots represent specific mutations of drug resistance genes. Green dots represent dhfr (N51I, C59R, S108N); blue dots represent mdr1 (N86Y, Y184F); red dots represent crt (M74I, N75D, N75K, K76T, A220S, Q271E, I356T, R371I); yellow dots represent dhps (S436A, G437A, K540E, A581G, A613S)

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Malaria Journal

ISSN: 1475-2875

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