Evidence of metabolic mechanisms playing a role in multiple insecticides resistance in Anopheles stephensi populations from Afghanistan

Safi, Noor Halim Zahid; Ahmadi, Abdul Ali; Nahzat, Sami; Ziapour, Seyyed Payman; Nikookar, Seyed Hassan; Fazeli-Dinan, Mahmoud; Enayati, Ahmadali; Hemingway, Janet

doi:10.1186/s12936-017-1744-9

Table 2 Descriptive analysis of the results of the biochemical assays performed on An. stephensi populations from Afghanistan in 2016

From: Evidence of metabolic mechanisms playing a role in multiple insecticides resistance in Anopheles stephensi populations from Afghanistan

		N	Mean	Std. deviation	Std. error	95% confidence interval for mean		Minimum	Maximum
		N	Mean	Std. deviation	Std. error	Lower bound	Upper bound	Minimum	Maximum
Descriptives
Alpha	1.0	90	0.000606935	0.0002243546	0.0000236491	0.000559945	0.000653926	0.0000613	0.0012599
	2.0	90	0.000882944	0.0004391187	0.0000462872	0.000790972	0.000974915	0.0001749	0.0026900
	3.0	90	0.001281330	0.0004898449	0.0000516342	0.001178734	0.001383926	0.0004359	0.0025958
	Total	270	0.000923736	0.0004865769	0.0000296121	0.000865435	0.000982037	0.0000613	0.0026900
Beta	1.0	90	0.000560930	0.0002256270	0.0000237832	0.000513674	0.000608187	0.0000217	0.0012485
	2.0	90	0.000912961	0.0005289397	0.0000557551	0.000802176	0.001023745	0.0000624	0.0027933
	3.0	90	0.001039151	0.0003281376	0.0000345887	0.000970423	0.001107878	0.0004121	0.0018416
	Total	270	0.000837681	0.0004314334	0.0000262562	0.000785987	0.000889374	0.0000217	0.0027933
GST	1.0	90	0.094644126	0.0445931787	0.0047005338	0.085304266	0.103983987	0.0057680	0.2404168
	2.0	90	0.125687826	0.0334270256	0.0035235179	0.118686671	0.132688981	0.0602100	0.1936805
	3.0	90	0.170861991	0.0906375391	0.0095540355	0.151878326	0.189845656	0.0100789	0.4758752
	Total	270	0.130397981	0.0687645517	0.0041848773	0.122158703	0.138637260	0.0057680	0.4758752
P450s	1.0	90	0.000056364	0.0000468496	0.0000049384	0.000046551	0.000066176	0.0000001	0.0002452
	2.0	90	0.000126040	0.0000635588	0.0000066997	0.000112728	0.000139352	0.0000297	0.0003423
	3.0	90	0.000143667	0.0000744365	0.0000078463	0.000128077	0.000159257	0.0000215	0.0004290
	Total	270	0.000108690	0.0000729523	0.0000044397	0.000099949	0.000117431	0.0000001	0.0004290
pNPA	1.0	90	0.180557226	0.1103588829	0.0116328477	0.157443005	0.203671446	0.0018530	0.5062369
	2.0	90	0.292412987	0.2596860355	0.0273733116	0.238022800	0.346803174	0.0043444	1.6858418
	3.0	90	0.316713874	0.1764954792	0.0186042570	0.279747611	0.353680136	0.0454042	0.7121251
	Total	270	0.263228029	0.2004405133	0.0121984212	0.239211509	0.287244548	0.0018530	1.6858418
aAChE	1.0	90	70.977705297	9.5683676804	1.0085945120	68.973649485	72.981761109	50.3058104	97.2588297
	2.0	90	56.690061678	12.527164551	1.3204792875	54.066297460	59.313825895	9.8746867	84.2042755
	3.0	90	51.579518613	23.323592773	2.4585221776	46.694487414	56.464549812	0.1056745	98.8008065
	Total	270	59.749095196	18.161457650	1.1052703914	57.573014562	61.925175830	0.1056745	98.8008065

1 Beech susceptible strain, 2 Kunar population, 3 Nangarhar population, alpha alpha esterase, beta beta esterase, GST glutathione S-transferase, P450s cytochrome P450s, pNPA para nitrophenyl acetate

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