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Table 2 Effect of hydroalcoholic crude root extract of Indigofera spicata on packed cell volume and body weight of infected mice in the 4 day suppressive test

From: Antiplasmodial activity of Indigofera spicata root extract against Plasmodium berghei infection in mice

Group

PCV

MBW

D0

D4

% change

D0

D4

% change

NS

53.56 ± 0.81

49.92 ± 1.34

−6.80

26.28 ± 0.51

24.36 ± 0.64

−7.31

200 mg/kg IS

53.08 ± 0.77

50.54 ± 1.91

−4.79

26.48 ± 1.2

25.42 ± 1.01

−4.00

400 mg/kg IS

53.56 ± 0.79

52.32 ± 1.25

−2.32

26.26 ± 0.77

25.68 ± 0.6

−2.21

600 mg/kg IS

53.0 ± 0.55

52.28 ± 0.76

−1.36

25.96 ± 1.13

25.42 ± 0.91

−2.08

25 mg/kg CQ

53.68 ± 0.72

54.22 ± 1.22a,2,b,2

1.01

26.84 ± 0.97

27.32 ± 1.18

1.79

  1. Data are expressed as mean ± SEM; n = 5
  2. IS, Indigofera spictata; CQ, chloroquine; MBW, mean body weight
  3. aCompared to control
  4. bTo 200 mg/kg
  5. cTo 400 mg/kg
  6. dTo 600 mg/kg
  7. 1p < 0.05
  8. 2p < 0.01
  9. 3p < 0.001
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Malaria Journal

ISSN: 1475-2875

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