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Table 1 Patient characteristics on admission

From: Safety and tolerability of adjunctive rosiglitazone treatment for children with uncomplicated malaria

 

Placebo, N = 10

Rosiglitazone, N = 20

p

Female sex (%)

7 (70%)

11 (55%)

0.70

Age (years)a

8 (4.6, 9.1)

6.9 (4.7, 9.8)

0.92

Weight (kg)

21.5 [15.0, 24.8]

20.2 [16.1, 2.7]

0.87

Height (cm)

124.0 [101.0, 132.5]

115.0 [106.0, 131.5]

0.75

BMI/age

−1.13 [−1.40, −0.37]

−0.15 [−3.2, 0.24]

0.11

Weight-for-age Z score (WAZ)

−1.1 [−1.4, −0.73]

−0.67 [−1.5, 0.81]

0.34

Temperature (oC)

38.3 [36.6, 39.1]

36.6 [36.1, 37.5]

0.07

Heart rate (bpm)

123.2 (15.58)

120.1 (14.6)

0.60

Glucose (mmol/L)

7.2 [5.3, 8.3]

5.9 [5.1, 7.3]

0.40

Lactate (mmol/L)

2.5 [2.1, 2.9]

1.9 [1.8, 3.2]

0.23

Haemoglobin (g/L)

10.1 (0.8)

10.1 (1.5)

0.99

Haematocrit (%)

30.1 (2.3)

30.4 (4.0)

0.83

Leukocytes (×109/L)

8.3 (3.0)

7.4 (2.5)

0.41

Platelets (×109/L)

96.3 (34.3)

131.8 (59.4)

0.09

AST (U/L)

53.8 (41.7)

36.4 (10.5)

0.08

ALT (U/L)

27.5 [5.3, 41.0]

33 [26, 36.8]

0.54

Urea (mg/dL)

12.5 [12.0, 17.3]

14.0 [13.0, 15.8]

0.67

Creatinine (µmol/L)

35.3 [30.7, 39.0]

31.2 [29.8, 42.8]

0.81

Parasite density (parasites/μL)

23,499 {4166, 55,491}

24,622 {3346, 91,869}

0.91

  1. Median [IQR] for non-normally distributed variables
  2. Number (%) for categorical variables
  3. Parasite density is represented as geometric mean {range}
  4. aMean (SD) for normally distributed variables