Table 1 Performance comparison of P-Genus FISH and Giemsa microscopy against qRT-PCR for the detection of malaria parasites in clinical samples
Sensitivity % (95% CI) | Specificity % (95% CI) | Predictive value | Likelihood ratio | Methods agreement % | K-value | |||
|---|---|---|---|---|---|---|---|---|
Positive test % (95% CI) | Negative test % (95% CI) | Positive test % (95% CI) | Negative test % (95% CI) | |||||
P-Genus FISH | 29.3 (23.8–35.3) | 75.8 (69.9–81.1) | 56.0 (47.1–64.5) | 50.5 (45.3–55.8) | 1.21 (0.90–1.62) | 0.93 (0.84–1.04) | 52.0 | 0.051 |
Microscopy | 58.2 (51.9–64.3) | 93.0 (89.1–95.9) | 89.8 (84.1–93.9) | 68.0 (62.7–72.9) | 8.35 (5.22–13.37) | 0.45 (0.39–0.52) | 75.2 | 0.508 |