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Table 4 The presence of fungus has minimal effect on the detection of P. falciparum and P. vivax from Whatman 3MM dried blood spots (DBS) compared to paired preserved capillary blood and Whatman 903 Protein Saver cards

From: A novel method for extracting nucleic acids from dried blood spots for ultrasensitive detection of low-density Plasmodium falciparum and Plasmodium vivax infections

Sample#

Blood

903 DBS

3MM DBS

Malaria

Malaria

Fungus

Malaria

Fungus

1

Pf+

Pf+

None

Pf+

Slight

2

Pv+, Pf+

Pv+, Pf+

None

Pv+, Pf+

Slight

3

Pv+

Pv+

None

Pv+

Slight

4

Pv+

Pv+

None

Pv+

Slight

5

Pv+

Pv+

None

Negative

Slight

6

Pf+

Pf+

None

Pf+

Slight

7

Pv+

Pv+

None

Pv+

Slight

8

Pf+

Pf+

None

Pf+

Moderate

9

Pv+

Pv+

None

Pv+

Moderate

10

Pf+

Pf+

None

Pf+

Moderate

11

Pv+

Pv+

None

Pv+

Moderate

12

Pv+, Pf+

Pv+, Pf+

None

Pv+, Pf+

Moderate

13

Pv+

Pv+

None

Pv+

Severe

14

Pv+, Pf+

Pv+, Pf+

None

Pv+, Pf+

Severe

15

Pv+

Pv+

None

Pv+

Severe

  1. # Individual study participant; Pf, P. falciparum; Pv, P. vivax; +, positive; 903 DBS, Whatman 903 Protein Saver dried blood spot; 3MM DBS, Whatman 3MM dried blood spot