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Fig. 8 | Malaria Journal

Fig. 8

From: Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates

Fig. 8Fig. 8

Pvdhfr and Pvdhps genotypes by year and area. a Proportion of pvdhfr 57L/I, 58R, 61M, 117N/T and 173F mutations, b proportion of pvdhps 382F/A/C, 383G, 399I, 512N, 585G, 553G, 555R, 585G, and 661V mutations, c proportion of the pvdhfr and pvdhps haplotypes. Pv: P. vivax; dhfr: dihydrofolate reductase; dhps: dihydropteroate synthase; wt: wild type. The international codes of areas were used. DL Delhi, GA Goa, HR Haryana. In a, sample size was different for each area. DL (n = 8, 32, 22, and 20 in years 2008, 2017, 2018 and 2019), GA (n = 22), HR (n = 13). In b, sample size was different for each area. DL (n = 28, 42, 22, and 12 in years 2008, 2017, 2018 and 2019), GA (n = 22). In c wild alleles are in lower case and mutant alleles are in upper case. The map depicted here is taken from official website of Ministry of External Affairs, Government of India (https://mea.gov.in/india-at-glance.htm, accessed 15/11/2021)

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Malaria Journal

ISSN: 1475-2875

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