Table 3 Effect of the total mg/kg dose administered on the risk of Plasmodium vivax recurrence between days 7 and 90 in patients with information on the total mg/kg dose administered
Adherence by total mg/kg dose administered | Overall risk of recurrence between days 7 and 90 | Risk of recurrence between days 7 and 56 | Risk of recurrence between days 56 and 90 | ||||||
|---|---|---|---|---|---|---|---|---|---|
Number of recurrences (Number of patients) † | Adjusted HR* (95% CI) | p-value | Number of recurrences (Number of patients) | Adjusted HR* (95% CI) | p-value | Number of recurrences (Number of patients) | Adjusted HR* (95% CI) | p-value | |
≥ 90% | 127 (3231) | Ref. | . | 49 (691) | Ref. | . | 78 (2540) | Ref. | . |
> 50- < 90% | 10 (81) | 3.2 (1.5–6.7) | 0.003 | 2 (38) | 1.11 (0.3–4.8) | 0.884 | 8 (43) | 6.0 (2.6–13.9) | < 0.001 |
≤ 50% | 16 (311) | 7.6 (1.9–30.0) | 0.004 | 14 (253) | 10.1 (1.9–52.5) | 0.006 | 2 (58) | 3.3 (0.3–38.6) | 0.336 |