| Total IgG (%) | IgG1 (%) | IgG2a (%) | IgG2b (%) | IgG3 (%) |
---|
cd-HAP | 21 | 56 | 25 | 24 | 7 |
cd-HAP + CpG | 22 | 68 | 32 | 30 | 31 |
cd-HAP + MPL | 15 | 63 | 18 | 21 | 11 |
cd-HAP + QS-21 | 44 | 85 | 55 | 40 | 43 |
cd-HAP + CMQ | 49 | 82 | 60 | 44 | 42 |
- The AI was determined by dividing the OD value of urea-treated serum samples by that of untreated samples, after substracting the OD of NMS (background), then multiplying by 100. Antibodies with AI values less than 30%, between 30 and 50%, and above 50% were considered low-avidity, intermediate-avidity, and high-avidity, respectively [27]