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Table 1 Clinico-epidemiological characteristics and classification of treatment outcome of patients with recurrent infections

From: msp1, msp2, and glurp genotyping to differentiate Plasmodium falciparum recrudescence from reinfections during prevention of reestablishment phase, Sri Lanka, 2014–2019

Patient Number

1

2

3

4

5

6

Age

46

35

30

40

40

46

Gender

F

M

M

M

M

M

Initial infection

 History of travel

Congo

Mozambique

Madagascar

Uganda

Congo

Central African Republic (CAR)

 Days from the onset of symptoms to diagnosis

7*

1

3

7

5

27*

 Days between arrival to diagnosis

5

9

7

13

14

11

 Parasitaemia (No. of parasites/µL)

73,098

12,286

139,144

25,800

84,400

176

 Clearance of parasitaemia

D1

D1

D2

D2

D2

D1

 Whether reactive surveillance conducted

Yes

Yes

Yes

Yes

Yes

Yes

Recurrent infection

 Re appearance of parasitaemia

D16

D19

D19

D28

D18

D105

 Parasitaemia (µL−1)

64

7,640

6,613

14,145

13,200

1,415

 Clearance of parasitaemia

D1

D1

D2

D2

D2

D2

 History of travel

No

No

No

No

No

Yes (CAR)

 Risk of importation

High

High

High

Moderate

High

High

 Receptivity in the area

Low

Low

Low

High

Low

Moderate

 Whether reactive surveillance conducted

Only travel contacts screened

Only travel contacts screened

Only travel contacts screened

Only travel contacts screened

Both travel and geographical contacts

Both travel and geographical contacts

 Classification of recurrent infection

LCF/recrudescence

LCF/recrudescence

LCF/recrudescence

LCF/recrudescence

LCF/recrudescence

Reinfection

  1. *These patients had onset of symptoms before the arrival to the country