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Table 2 Parasitological and clinical outcomes of enrolled patients

From: Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in mainland Tanzania, 2018

Outcome

Kibaha (n = 83)

Mlimba (n = 85)

Mkuzi (n = 88)

Ujiji (n = 88)

n (%)

95%CI

n (%)

95%CI

n (%)

95%CI

n (%)

95%CI

PCR Uncorrected

 ETF

0

–

0

–

0

–

0

–

 LCF

8 (9.6)

4.9–18.2

3 (3.5)

1.1–10.5

8 (9.1)

4.6–17.2

6 (6.8)

3.1–14.5

 LPF

4 (4.8)

1.8–12.2

9 (10.6)

5.6–19.2

23 (26.1)

18–36.4

17 (19.3)

12.3–29

 ACPR

71 (85.5)

76.1–91.6

73 (85.9)

76.7–91.8

57 (64.8)

54.2–74.1

65 (73.9)

63.6–82

 Total

83

 

85

 

88

 

88

 

 Excluded

        

 Withdrawn/lost

2

 

3

 

0

 

0

 

 Cumulative cure rate

85.6

76.0–91.5

85.9

76.5–91.7

64.8

53.8–73.7

73.9

63.3–81.8

PCR Corrected

 ETF

0

–

0

–

0

–

0

–

 LCF

1 (1.4)

0.2–9.4

0

–

0

–

0

–

 LPF

1(1.4)

–

0

–

1 (1.7)

0.2–11.5

1 (1.5)

0.2–10.2

 ACPR

71 (97.3)

90.6–99.8

73 (100)

–

57 (98.3)

88.5–99.8

65 (98.5)

89.8–99.8

 Total

73

 

73

 

58

 

66

 

 Excluded

        

 Reinfections

10

 

11

 

28

 

21

 

 PCR unknown

0

 

1

 

1

 

1

 

 Missing PCR

0

 

0

 

1

 

0

 

 Withdrawn/lost

2

 

3

 

0

 

0

 

 Cumulative cure rate

(Kaplan–Meier)

97.6

90.5–99.4

100

-

98.6

90.7–99.8

98.8

91.9–99.8

  1. ETF Early Treatment Failure, LPF Late Parasitological Response, LCF Late Clinical Failure, ACPR Adequate Clinical and Parasitological Response