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Table 1 Comparison of antibody titres and prevalence measured in plasma and saliva against MSP-119 and AMA-1 P. falciparum merozoite surface antigens

From: Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum

 

Tanzania (n = 53)

The Gambia (n = 200)

Antigen

Plasma

Saliva

Oracol

Saliva

Orasure

Plasma

Saliva

AMA-1

R2

 

0.89

0.93

 

0.64

Mean response (range)

138

(1-817)

148

(3-902)

108*

(0-871)

317

(0-917)

185*

(45-818)

% positive

47

34

36

36

30

MSP-1 19

r2

 

0.75

0.93

 

0.63

Mean response (range)

61

(0-769)

62

(0-625)

37*

(0-610)

229

(0-844)

113*

(0-612)

% positive

28

26

15

30

20

  1. * = significant difference between means of titre response in saliva and plasma using t-test
  2. ND not done