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Table 1 Comparison of antibody titres and prevalence measured in plasma and saliva against MSP-119 and AMA-1 P. falciparum merozoite surface antigens

From: Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum

  Tanzania (n = 53) The Gambia (n = 200)
Antigen Plasma Saliva Oracol Saliva Orasure Plasma Saliva
AMA-1 R2   0.89 0.93   0.64
Mean response (range) 138 (1-817) 148 (3-902) 108* (0-871) 317 (0-917) 185* (45-818)
% positive 47 34 36 36 30
MSP-1 19 r2   0.75 0.93   0.63
Mean response (range) 61 (0-769) 62 (0-625) 37* (0-610) 229 (0-844) 113* (0-612)
% positive 28 26 15 30 20
  1. * = significant difference between means of titre response in saliva and plasma using t-test
  2. ND not done