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  1. Content type: Research

    Macaca fascicularis (long-tailed macaque) is the most widespread species of macaque in Southeast Asia and the only species of monkey found naturally in the Philippines. The species is the natural host for the zoo...

    Authors: Lief Erikson Gamalo, Judeline Dimalibot, Khamisah Abdul Kadir, Balbir Singh and Vachel Gay Paller

    Citation: Malaria Journal 2019 18:147

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  2. Content type: Research

    Plasmodium falciparum parasite is the most deadly species of human malaria, and the development of an effective vaccine that prevents P. falciparum infection and transmission is a key target for malarial eliminat...

    Authors: Sakineh Pirahmadi, Sedigheh Zakeri, Akram A. Mehrizi, Navid D. Djadid, Abbas-Ali Raz, Jafar J. Sani, Ronak Abbasi and Zahra Ghorbanzadeh

    Citation: Malaria Journal 2019 18:146

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  3. Content type: Research

    The trend analysis of malaria data from health facilities is useful for understanding dynamics of malaria epidemiology and inform for future malaria control planning. Changes in clinical malaria characteristic...

    Authors: Dawit Hawaria, Hallelujah Getachew, Guofa Zhong, Assalif Demissew, Kasahun Habitamu, Beka Raya, Ming-Chieh Lee, Delenasaw Yewhalaw and Guiyun Yan

    Citation: Malaria Journal 2019 18:145

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  4. Content type: Research

    Malaria in pregnancy is a major public health challenge, but its risk factors remain poorly understood in some settings. This study assessed the association between household and maternal characteristics and m...

    Authors: Jaffer Okiring, Peter Olwoch, Abel Kakuru, Joseph Okou, Harriet Ochokoru, Tedy Andra Ochieng, Richard Kajubi, Moses R. Kamya, Grant Dorsey and Lucy S. Tusting

    Citation: Malaria Journal 2019 18:144

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  5. Content type: Research

    In malaria-endemic settings, a small proportion of children suffer repeated malaria infections, contributing to most of the malaria cases, yet underlying factors are not fully understood. This study was aimed ...

    Authors: Jaden Bendabenda, Noel Patson, Lotta Hallamaa, Ulla Ashorn, Kathryn G. Dewey, Per Ashorn and Kenneth Maleta

    Citation: Malaria Journal 2019 18:143

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  6. Content type: Correction

    Following publication of the original article [1], the author has flagged errors that affect the scientific content of the article.

    Authors: Tarekegn Solomon, Eskindir Loha, Wakgari Deressa, Meshesha Balkew, Taye Gari, Hans J. Overgaard and Bernt Lindtjørn

    Citation: Malaria Journal 2019 18:142

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    The original article was published in Malaria Journal 2018 17:239

  7. Content type: Research

    Conflicting results exist on the added benefit of combining long-lasting insecticidal nets (LLINs) with indoor residual spraying (IRS) to control malaria infection. The main study objective was to evaluate whe...

    Authors: Eskindir Loha, Wakgari Deressa, Taye Gari, Meshesha Balkew, Oljira Kenea, Tarekegn Solomon, Alemayehu Hailu, Bjarne Robberstad, Meselech Assegid, Hans J. Overgaard and Bernt Lindtjørn

    Citation: Malaria Journal 2019 18:141

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  8. Content type: Research

    Primaquine, an 8-aminoquinoline with anti-hypnozoite activity against Plasmodium vivax, is metabolized by human cytochrome P450 2D6 (CYP2D6) to its active metabolite. Human CYP2D6 activities may influence the met...

    Authors: Nanhua Chen, Simone Dowd, Michelle L. Gatton, Alyson Auliff, Michael D. Edstein and Qin Cheng

    Citation: Malaria Journal 2019 18:140

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  9. Content type: Research

    The World Health Organization (WHO) recommends combinations of an artemisinin derivative plus an anti-malarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infections. In ...

    Authors: Monia Guidi, Thomas Mercier, Manel Aouri, Laurent A. Decosterd, Chantal Csajka, Bernhards Ogutu, Gwénaëlle Carn and Jean-René Kiechel

    Citation: Malaria Journal 2019 18:139

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  10. Content type: Research

    Naturally acquired immunity to malaria across the globe varies in intensity and protective powers. Many of the studies on immunity are from hyperendemic regions of Africa. In Asia, particularly in India, there...

    Authors: Apoorva Venkatesh, Aarti Jain, Huw Davies, Ligia Periera, Jennifer N. Maki, Edwin Gomes, Philip L. Felgner, Sanjeeva Srivastava, Swati Patankar and Pradipsinh K. Rathod

    Citation: Malaria Journal 2019 18:138

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  11. Content type: Correction

    Following publication of the original article [1], it was flagged that the name of the author Lisa Ranford-Cartwright had been (incorrectly) given as ‘Lisa-Ranford Cartwright.

    Authors: Marta F. Maia, Melissa Kapulu, Michelle Muthui, Martin G. Wagah, Heather M. Ferguson, Floyd E. Dowell, Francesco Baldini and Lisa Ranford-Cartwright

    Citation: Malaria Journal 2019 18:137

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    The original article was published in Malaria Journal 2019 18:85

  12. Content type: Case report

    Limited health research capacities (HRC) undermine a country’s ability to identify and adequately respond to local health needs. Although numerous interventions to strengthen HRC have been conducted in Africa,...

    Authors: Alfredo Mayor, Guillermo Martínez-Pérez, Christine K. Tarr-Attia, Bondey Breeze-Barry, Adelaida Sarukhan, Ana Meyer García-Sípido, Juan Carlos Hurtado, Dawoh Peter Lansana and Núria Casamitjana

    Citation: Malaria Journal 2019 18:136

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  13. Content type: Research

    The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed species identification and characterization for effective malaria vector surveillance. Molecula...

    Authors: Tamar E. Carter, Solomon Yared, Shantoy Hansel, Karen Lopez and Daniel Janies

    Citation: Malaria Journal 2019 18:135

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  14. Content type: Research

    Malaria is an increasing concern in Indonesia. Socio-demographic factors were found to strongly influence malaria prevalence. This research aimed to explore the associations between socio-demographic factors a...

    Authors: Hamzah Hasyim, Pat Dale, David A. Groneberg, Ulrich Kuch and Ruth Müller

    Citation: Malaria Journal 2019 18:134

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  15. Content type: Research

    In 2006, artemether–lumefantrine (ALU), specifically Coartem® (Novartis Pharma AG, Basel Switzerland), was approved as the first-line drug for treatment of uncomplicated malaria in Tanzania. Due to poor availabil...

    Authors: Manase Kilonzi, Omary Minzi, Ritah Mutagonda, Philip Sasi, Appolinary Kamuhabwa and Eleni Aklillu

    Citation: Malaria Journal 2019 18:133

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  16. Content type: Research

    Heat shock proteins (HSPs) are molecular chaperones that are involved in many normal cellular processes and various kinds of environmental stress. There is still no report regarding the diversity and phylogene...

    Authors: Feng-Ling Si, Liang Qiao, Qi-Yi He, Yong Zhou, Zhen-Tian Yan and Bin Chen

    Citation: Malaria Journal 2019 18:132

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  17. Content type: Research

    Anopheles sinensis is the primary vector of vivax malaria in China and its control is under great threat as the development of insecticide resistance. In contrast to physiological resistance, there is no report o...

    Authors: Zhengbo He, Jing Zhang, Zongpan Shi, Jingang Liu, Jingjing Zhang, Zhentian Yan and Bin Chen

    Citation: Malaria Journal 2019 18:131

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  18. Content type: Research

    Zambia continues to make strides in reducing malaria burden through the use of proven malaria interventions and has recently pledged to eliminate malaria by 2021. Case management services have been scaled up a...

    Authors: Lungowe Sitali, John M. Miller, Mulenga C. Mwenda, Daniel J. Bridges, Moonga B. Hawela, Busiku Hamainza, Elizabeth Chizema-Kawesha, Thomas P. Eisele, James Chipeta and Bernt Lindtjørn

    Citation: Malaria Journal 2019 18:130

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  19. Content type: Research

    Avian haemosporidia are obligate blood parasites with an ample range of hosts worldwide. To understand how host communities may influence the diversity of parasites of the neotropics, the spatial genetic varia...

    Authors: Diana Lorena Gil-Vargas and Raul Ernesto Sedano-Cruz

    Citation: Malaria Journal 2019 18:129

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  20. Content type: Research

    Plasmodium falciparum-infected erythrocytes (IE) sequester in deep vascular beds where their adhesion is mediated by an array of endothelial surface receptors. Because parasite adhesion has been associated with d...

    Authors: Oumar Attaher, Almahamoudou Mahamar, Bruce Swihart, Amadou Barry, Bacary S. Diarra, Moussa B. Kanoute, Adama B. Dembele, Sekouba Keita, Santara Gaoussou, Djibrilla Issiaka, Alassane Dicko, Patrick E. Duffy and Michal Fried

    Citation: Malaria Journal 2019 18:128

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  21. Content type: Research

    Insecticide resistance in Anopheles coluzzii mosquitoes has become widespread throughout West Africa including in Burkina Faso. The insecticide resistance allele (kdr or L1014F) is a prime indicator that is highl...

    Authors: Mark J. Hanemaaijer, Hannah Higgins, Ipek Eralp, Youki Yamasaki, Norbert Becker, Oscar D. Kirstein, Gregory C. Lanzaro and Yoosook Lee

    Citation: Malaria Journal 2019 18:127

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  22. Content type: Research

    Today, the development of new and well-tolerated anti-malarial drugs is strongly justified by the emergence of Plasmodium falciparum resistance. In 2014–2015, a phase 2b clinical study was conducted to evaluate t...

    Authors: Didier Leroy, Fiona Macintyre, Yeka Adoke, Serge Ouoba, Aissata Barry, Ghyslain Mombo-Ngoma, Jacques Mari Ndong Ngomo, Rosauro Varo, Yannelle Dossou, Antoinette Kitoto Tshefu, Tran Thanh Duong, Bui Quang Phuc, Bart Laurijssens, Roland Klopper, Nimol Khim, Eric Legrand…

    Citation: Malaria Journal 2019 18:126

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  23. Content type: Correction

    Following publication of the original article [1], the corresponding author flagged that the particle ‘de’ in their name had been placed incorrectly.

    Authors: Jessica de Oliveira Sousa, Bernardino Claudio de Albuquerque, José Rodrigues Coura and Martha Cecilia Suárez-Mutis

    Citation: Malaria Journal 2019 18:125

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    The original article was published in Malaria Journal 2019 18:100

  24. Content type: Research

    In low malaria transmission areas, many people acquire multiple malaria infections within a single season. This study aimed to describe the pattern and epidemiological profile of malaria recurrence in a hypoen...

    Authors: Saranath Lawpoolsri, Jetsumon Sattabongkot, Jeeraphat Sirichaisinthop, Liwang Cui, Kirakorn Kiattibutr, Nattawan Rachaphaew, Kritsana Suk-uam, Amnat Khamsiriwatchara and Jaranit Kaewkungwal

    Citation: Malaria Journal 2019 18:124

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  25. Content type: Commentary

    Delayed haemolysis is a frequent adverse event after treatment with artesunate (AS). Removing once-infected “pitted” erythrocytes by the spleen is the most accepted mechanism of haemolysis in these cases. Howe...

    Authors: Daniel Camprubí, Arturo Pereira, Natalia Rodriguez-Valero, Alex Almuedo, Rosauro Varo, Climent Casals-Pascual, Quique Bassat, Denis Malvy and Jose Muñoz

    Citation: Malaria Journal 2019 18:123

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  26. Content type: Research

    To reduce the malaria burden in Nigeria, the National Malaria Strategic Plan (NMSP) 2014‒2020 calls for the scale-up of prevention and treatment interventions, including social and behaviour change (SBC). SBC ...

    Authors: Kirsten Zalisk, Samantha Herrera, Uwem Inyang, Audu Bala Mohammed, Perpetua Uhomoibhi and Yazoumé Yé

    Citation: Malaria Journal 2019 18:121

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  27. Content type: Research

    Mosquitoes of the Anopheles gambiae complex are the main malaria vectors worldwide. Due to the lack of a vaccine to prevent malaria, the principal way to reduce the impact of this disease relies on the use of che...

    Authors: Derciliano Lopes da Cruz, Marcelo Henrique Santos Paiva, Duschinka Ribeiro Duarte Guedes, Joana Alves, Lara Ferrero Gómez and Constância Flávia Junqueira Ayres

    Citation: Malaria Journal 2019 18:120

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  28. Content type: Research

    Traditional medicinal plants are one of the potential sources of anti-malarial drugs and there is an increasing interest in the use and development of traditional herbal remedies for the treatment of malaria a...

    Authors: Prisca A. Kweyamba, Denis Zofou, Noella Efange, Jules-Clement N. Assob, Jovin Kitau and Mramba Nyindo

    Citation: Malaria Journal 2019 18:119

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  29. Content type: Research

    Malaria is still an important parasitic infectious disease that affecting poor and vulnerable communities in many developing countries, including Indonesia. During the period of 2010–2017, there have been appr...

    Authors: Pandji Wibawa Dhewantara, Mara Ipa and Mutiara Widawati

    Citation: Malaria Journal 2019 18:118

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  30. Content type: Research

    Brazilian malaria control programmes successfully reduced the incidence and mortality rates from 2005 to 2016. Since 2017, increased malaria has been reported across the Amazon. Few field studies focus on the ...

    Authors: Maria Anice M. Sallum, Jan E. Conn, Eduardo S. Bergo, Gabriel Z. Laporta, Leonardo S. M. Chaves, Sara A. Bickersmith, Tatiane M. P. de Oliveira, Elder Augusto G. Figueira, Gilberto Moresco, Lêuda Olívêr, Claudio J. Struchiner, Laith Yakob and Eduardo Massad

    Citation: Malaria Journal 2019 18:117

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  31. Content type: Research

    Malaria remains a global public health problem responsible for 445,000 deaths in 2016. While microscopy remains the mainstay of malaria diagnosis, highly sensitive molecular methods for detection of low-grade ...

    Authors: Bryan Grabias, Edward Essuman, Isabella A. Quakyi and Sanjai Kumar

    Citation: Malaria Journal 2019 18:116

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  32. Content type: Research

    In Mozambique, the prevalence of malaria in children under 5 years of age is among the highest in the world, but limited data exist on determinants of care-seeking behaviour for malaria. This study aimed at de...

    Authors: Annette Cassy, Abuchahama Saifodine, Baltazar Candrinho, Maria do Rosário Martins, Saraiva da Cunha, Filomena Martins Pereira and Eduardo Samo Gudo

    Citation: Malaria Journal 2019 18:115

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  33. Content type: Research

    Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion...

    Authors: Jureeporn Duanguppama, Vivek Bhakta Mathema, Rupam Tripura, Nicholas P. J. Day, Mayfong Maxay, Chea Nguon, Lorenz von Seidlein, Mehul Dhorda, Thomas J. Peto, Francois Nosten, Nicholas J. White, Arjen M. Dondorp and Mallika Imwong

    Citation: Malaria Journal 2019 18:114

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  34. Content type: Research

    In the context of widespread mosquito resistance to currently available pesticides, novel, precise genetic vector control methods aimed at population suppression or trait replacement are a potentially powerful...

    Authors: Patric Stephane Epopa, Catherine Matilda Collins, Ace North, Abdoul Azize Millogo, Mark Quentin Benedict, Frederic Tripet and Abdoulaye Diabate

    Citation: Malaria Journal 2019 18:113

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  35. Content type: Research

    Physiological characteristics (age and blood feeding status) of malaria vectors can influence their susceptibility to the current vector control tools that target their feeding and resting behaviour. To ensure...

    Authors: Maxwell G. Machani, Eric Ochomo, David Sang, Mariangela Bonizzoni, Guofa Zhou, Andrew K. Githeko, Guiyun Yan and Yaw A. Afrane

    Citation: Malaria Journal 2019 18:112

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  36. Content type: Research

    Primaquine (PQ) prevents relapses of vivax malaria but may induce severe haemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient patients. Data on the safety of primaquine in infants are limited.

    Authors: Agus Setyadi, Eggi Arguni, Enny Kenangalem, Afdhal Hasanuddin, Daniel A. Lampah, Kamala Thriemer, Nicholas M. Anstey, Paulus Sugiarto, Julie A. Simpson, Ric N. Price, Nicholas M. Douglas and Jeanne R. Poespoprodjo

    Citation: Malaria Journal 2019 18:111

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  37. Content type: Research

    The mosquito Anopheles (Kerteszia) cruzii is the main vector of human and simian malaria in the Atlantic Forest. This species is usually abundant in the forests where it occurs, preferring to live and feed on can...

    Authors: Antônio Ralph Medeiros-Sousa, Rafael de Oliveira Christe, Ana Maria Ribeiro de Castro Duarte, Luis Filipe Mucci, Walter Ceretti-Junior and Mauro Toledo Marrelli

    Citation: Malaria Journal 2019 18:110

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  38. Content type: Research

    As part of ongoing co-surveillance of intestinal schistosomiasis and malaria in Ugandan school children, a non-invasive detection method for amplification of Plasmodium DNA using real-time (rt)PCR analysis of eth...

    Authors: Hajri Al-Shehri, B. Joanne Power, John Archer, Alice Cousins, Aaron Atuhaire, Moses Adriko, Moses Arinaitwe, Abdullah D. Alanazi, E. James LaCourse, Narcis B. Kabatereine and J. Russell Stothard

    Citation: Malaria Journal 2019 18:109

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  39. Content type: Research

    The South African province of KwaZulu-Natal is rapidly approaching elimination status for malaria with a steady decline in local cases. With the possibility of achieving elimination in reach, the KZN malaria c...

    Authors: Ryleen Balawanth, Inessa Ba, Bheki Qwabe, Laura Gast, Rajendra Maharaj, Jaishree Raman, Rebecca Graffy, Mbavhalelo Shandukani and Devanand Moonasar

    Citation: Malaria Journal 2019 18:108

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  40. Content type: Research

    Historically, malaria had been a widespread disease in China. A national plan was launched in China in 2010, aiming to eliminate malaria by 2020. In 2017, no indigenous cases of malaria were detected in China ...

    Authors: Shengjie Lai, Junling Sun, Nick W. Ruktanonchai, Sheng Zhou, Jianxing Yu, Isobel Routledge, Liping Wang, Yaming Zheng, Andrew J. Tatem and Zhongjie Li

    Citation: Malaria Journal 2019 18:107

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  41. Content type: Research

    Following the scale-up of intervention efforts, malaria burden has decreased dramatically in Solomon Islands (SI). Submicroscopic and asymptomatic Plasmodium vivax infections are now the major challenge for malar...

    Authors: Yi Wan Quah, Andreea Waltmann, Stephan Karl, Michael T. White, Ventis Vahi, Andrew Darcy, Freda Pitakaka, Maxine Whittaker, Daniel J. Tisch, Alyssa Barry, Celine Barnadas, James Kazura and Ivo Mueller

    Citation: Malaria Journal 2019 18:106

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  42. Content type: Research

    The World Health Organization (WHO) recommendation of treating uncomplicated malaria during the second and third trimester of pregnancy with an artemisinin-based combination therapy (ACT) has already been impl...

    Authors: Michael Nambozi, Halidou Tinto, Victor Mwapasa, Harry Tagbor, Jean-Bertin Bukasa Kabuya, Sebastian Hachizovu, Maminata Traoré, Innocent Valea, Marc Christian Tahita, Gifty Ampofo, Jozefien Buyze, Raffaella Ravinetto, Diana Arango, Kamala Thriemer, Modest Mulenga, Jean-Pierre van Geertruyden…

    Citation: Malaria Journal 2019 18:105

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  43. Content type: Research

    The Belgian Reference Laboratory for Plasmodium offers a free-of-charge reference testing of malaria-positive or doubtful samples to clinical laboratories.

    Authors: Laura Loomans, Anali Conesa Botella, Agnes D’hondt, Jacob Verschueren, Dorien Van den Bossche, Marjan Van Esbroeck and Jan Jacobs

    Citation: Malaria Journal 2019 18:104

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  44. Content type: Research

    Malaria is a leading cause of illness and death in Nigeria, but access of poor people to quality anti-malarial services remains low especially in the rural areas. Patent and proprietary medicine vendors (PPMVs...

    Authors: Oladimeji Oladepo, Abisoye S. Oyeyemi, Musibau A. Titiloye, Adedayo O. Adeyemi, Sarah M. Burnett, Iorwakwagh Apera, Opeyemi Oladunni and Michael Alliu

    Citation: Malaria Journal 2019 18:103

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  45. Content type: Research

    Malaria still claims substantial lives of individuals in Tanzania. Insecticide-treated nets (ITNs) and indoor residual spray (IRS) are used as major malaria vector control tools. These tools are facing great c...

    Authors: Deokary Joseph Matiya, Anitha B. Philbert, Winifrida Kidima and Johnson J. Matowo

    Citation: Malaria Journal 2019 18:102

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  46. Content type: Research

    Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the therapeutic efficacy of the SP. As molecular markers,

    Authors: Tingting Jiang, Jiangtao Chen, Hongxia Fu, Kai Wu, Yi Yao, Juan Urbano Monsuy Eyi, Rocio Apicante Matesa, Maximo Miko Ondo Obono, Weixing Du, Huabing Tan, Min Lin and Jian Li

    Citation: Malaria Journal 2019 18:101

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  47. Content type: Research

    The Tanzanian National Malaria Control Programme (NMCP) and its partners have been implementing regular therapeutic efficacy studies (TES) to monitor the performance of different drugs used or with potential u...

    Authors: Celine I. Mandara, Filbert Francis, Mercy G. Chiduo, Billy Ngasala, Renata Mandike, Sigsbert Mkude, Frank Chacky, Fabrizio Molteni, Ritha Njau, Ally Mohamed, Marian Warsame and Deus S. Ishengoma

    Citation: Malaria Journal 2019 18:99

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  48. Content type: Research

    Microscopic detection of malaria parasites is the standard method for clinical diagnosis of malaria in Brazil. However, malaria epidemiological surveillance studies specifically aimed at the detection of low-d...

    Authors: Heather M. Kudyba, Jaime Louzada, Dragan Ljolje, Karl A. Kudyba, Vasant Muralidharan, Joseli Oliveira-Ferreira and Naomi W. Lucchi

    Citation: Malaria Journal 2019 18:98

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  49. Content type: Research

    Lactic acidosis with an elevated lactate–pyruvate ratio suggesting anoxia is a common feature of severe falciparum malaria. High lactate levels are associated with parasitized erythrocyte sequestration in the ...

    Authors: Hugh W. Kingston, Aniruddha Ghose, Voravut Rungpradubvong, M. Trent Herdman, Katherine Plewes, Haruhiko Ishioka, Stije J. Leopold, Richard J. Maude, Benjamas Intharabut, Sanjib Mohanty, Nicholas P. J. Day, Nicholas J. White, Md Amir Hossain, Nicholas M. Anstey and Arjen M. Dondorp

    Citation: Malaria Journal 2019 18:97

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