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  1. Following publication of the original article [1], the authors flagged an error in Addition file 6.

    Authors: Aayush Khadka, Nicole A. Perales, Dorothy J. Wei, Anna D. Gage, Noah Haber, Stéphane Verguet, Bryan Patenaude and Günther Fink

    Citation: Malaria Journal 2019 18:365

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2018 17:224

  2. Long-lasting insecticidal nets (LLIN), improved diagnosis and artemisinin-based combination therapy (ACT) have reduced malaria prevalence in Papua New Guinea since 2008. Yet, national incidence trends are inco...

    Authors: Daniela Rodriguez-Rodriguez, Seri Maraga, Lina Lorry, Leanne J. Robinson, Peter M. Siba, Ivo Mueller, Justin Pulford, Amanda Ross and Manuel W. Hetzel

    Citation: Malaria Journal 2019 18:364

    Content type: Research

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  3. Improving maternal health remains a priority to the Ghanaian government. Consequently, it has implemented the World Health Organization recommendation of distributing free long-lasting insecticidal nets (LLINs...

    Authors: Matilda Aberese-Ako, Pascal Magnussen, Gifty D. Ampofo and Harry Tagbor

    Citation: Malaria Journal 2019 18:363

    Content type: Research

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  4. Interventions to raise community awareness about malaria prevention and treatment have used various approaches with little evidence on their efficacy. This study aimed to determine the effectiveness of loudspe...

    Authors: Pyae Linn Aung, Tepanata Pumpaibool, Than Naing Soe, Jessica Burgess, Lynette J. Menezes, Myat Phone Kyaw and Liwang Cui

    Citation: Malaria Journal 2019 18:362

    Content type: Research

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  5. Drug resistance is one of the greatest challenges of malaria control programme in Mali. Recent advances in next-generation sequencing (NGS) technologies provide new and effective ways of tracking drug-resistan...

    Authors: Seidina A. S. Diakité, Karim Traoré, Ibrahim Sanogo, Taane G. Clark, Susana Campino, Modibo Sangaré, Djeneba Dabitao, Antoine Dara, Drissa S. Konaté, Fousseyni Doucouré, Amadou Cissé, Bourama Keita, Mory Doumbouya, Merepen A. Guindo, Mahamoudou B. Toure, Nafomon Sogoba…

    Citation: Malaria Journal 2019 18:361

    Content type: Research

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  6. Malaria remains a leading cause of morbidity and mortality in Mozambique. Increased investments in malaria control have reduced the burden, but few studies have estimated the costs of malaria in the country. T...

    Authors: Sergi Alonso, Carlos J. Chaccour, Eldo Elobolobo, Amilcar Nacima, Baltazar Candrinho, Abuchahama Saifodine, Francisco Saute, Molly Robertson and Rose Zulliger

    Citation: Malaria Journal 2019 18:360

    Content type: Research

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  7. A major health burden in Cameroon is malaria, a disease that is sensitive to climate, environment and socio-economic conditions, but whose precise relationship with these drivers is still uncertain. An improve...

    Authors: Amelie D. Mbouna, Adrian M. Tompkins, Andre Lenouo, Ernest O. Asare, Edmund I. Yamba and Clement Tchawoua

    Citation: Malaria Journal 2019 18:359

    Content type: Research

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  8. Insecticide resistance is a growing threat to malaria vector control. Ivermectin, either administered to humans or animals, may represent an alternate strategy to reduce resistant mosquito populations. The aim...

    Authors: Wondemeneh Mekuriaw, Meshesha Balkew, Louisa A. Messenger, Delenasaw Yewhalaw, Adugna Woyessa and Fekadu Massebo

    Citation: Malaria Journal 2019 18:357

    Content type: Research

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  9. Control and elimination of malaria can be accelerated by transmission-blocking interventions such as vaccines. A surface antigen of Plasmodium falciparum gametocytes, Pfs230, is a leading vaccine target antigen, ...

    Authors: Shwu-Maan Lee, Yimin Wu, John M. Hickey, Kazutoyo Miura, Neal Whitaker, Sangeeta B. Joshi, David B. Volkin, C. Richter King and Jordan Plieskatt

    Citation: Malaria Journal 2019 18:356

    Content type: Research

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  10. Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a vital role in improving malaria case management and surveillance particularly in Africa, where Plasmodium falciparum is predominant. ...

    Authors: Bosco B. Agaba, Adoke Yeka, Sam Nsobya, Emmanuel Arinaitwe, Joaniter Nankabirwa, Jimmy Opigo, Paul Mbaka, Chae Seung Lim, Joan N. Kalyango, Charles Karamagi and Moses R. Kamya

    Citation: Malaria Journal 2019 18:355

    Content type: Research

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  11. CareStart™ malaria HRP2/pLDH (Pf/pan) combo test is one of the several rapid diagnostic tests (RDT) approved for diagnosis of malaria at the point of care in Tanzania. However, there are limited studies on the...

    Authors: George M. Bwire, Billy Ngasala, Manase Kilonzi, Wigilya P. Mikomangwa, Fatuma F. Felician and Appolinary A. R. Kamuhabwa

    Citation: Malaria Journal 2019 18:354

    Content type: Research

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  12. Plasmodium falciparum drug resistance surveillance is key to successful disease control and eradication. Contemporary methods that only allow determination of prevalence of resistance are expensive, time consumin...

    Authors: Rebecca Smith-Aguasca, Himanshu Gupta, Estefania Uberegui, Mara Maquina, Francisco Saute, Krijn P. Paaijmans, Alfredo Mayor and Silvie Huijben

    Citation: Malaria Journal 2019 18:351

    Content type: Methodology

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  13. Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and rapid diagnostic tests. This is particularly true in surveillance of mal...

    Authors: Abu Naser Mohon, Sisay Getie, Nusrat Jahan, Mohammad Shafiul Alam and Dylan R. Pillai

    Citation: Malaria Journal 2019 18:350

    Content type: Research

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  14. The resistance of Plasmodium falciparum to artemisinin has been identified in Asia and some parts of Africa. The drug resistance of P. falciparum will be an obstacle to the successful elimination of malaria by 20...

    Authors: Jun Li, Yunliang Shi, Weiwei Zhang, Hui Yan, Kangming Lin, Shujiao Wei, Haiyan Wei, Yichao Yang, Shanping Huang, Yuxin Lu, Anxiang Ma and Jian Qin

    Citation: Malaria Journal 2019 18:349

    Content type: Research

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  15. Widespread elimination of malaria requires an ultra-sensitive detection method that can detect low parasitaemia levels seen in asymptomatic carriers who act as reservoirs for further transmission of the diseas...

    Authors: Philip Heraud, Patutong Chatchawal, Molin Wongwattanakul, Patcharaporn Tippayawat, Christian Doerig, Patcharee Jearanaikoon, David Perez-Guaita and Bayden R. Wood

    Citation: Malaria Journal 2019 18:348

    Content type: Research

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  16. Gene drive mosquitoes have been proposed as a possible means to reduce the transmission of malaria in Africa. Because this technology has no prior use-history at this time, environmental risk assessments for g...

    Authors: John L. Teem, Aggrey Ambali, Barbara Glover, Jeremy Ouedraogo, Diran Makinde and Andrew Roberts

    Citation: Malaria Journal 2019 18:347

    Content type: Research

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  17. Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel...

    Authors: Sonal Gupta, Juveria Khan, Priti Kumari, Chintam Narayana, R. Ayana, Malabika Chakrabarti, Ram Sagar and Shailja Singh

    Citation: Malaria Journal 2019 18:346

    Content type: Research

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  18. Malaria is a public health problem in the Brazilian Amazon region. In integrated vector management for malaria (anopheline) control, indoor residual spraying (IRS) represents one of the main tools in the basic...

    Authors: Ana Paula S. A. Corrêa, Allan K. R. Galardo, Luana A. Lima, Daniel C. P. Câmara, Josiane N. Müller, Jéssica Fernanda S. Barroso, Oscar M. M. Lapouble, Cynara M. Rodovalho, Kaio Augusto N. Ribeiro and José Bento P. Lima

    Citation: Malaria Journal 2019 18:345

    Content type: Research

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  19. Historically neglected, due to its biological peculiarities, the absence of a continuous long-term in vitro blood stage culture system and a propensity towards high morbidity rather than mortality, Plasmodium viv...

    Authors: Richard Thomson-Luque, John H. Adams, Clemens H. M. Kocken and Erica M. Pasini

    Citation: Malaria Journal 2019 18:344

    Content type: Review

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  20. A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium ...

    Authors: Moses N. Ikegbunam, Charles N. Nkonganyi, Bolaji N. Thomas, Charles O. Esimone, Thirumalaisamy P. Velavan and Olusola Ojurongbe

    Citation: Malaria Journal 2019 18:343

    Content type: Research

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  21. Chloroquine (CQ) was the drug of choice for decades in the treatment of falciparum malaria until resistance emerged. CQ is suggested to accumulate in the parasite’s digestive vacuole (DV), where it unfolds its...

    Authors: Sarah J. Reiling and Petra Rohrbach

    Citation: Malaria Journal 2019 18:342

    Content type: Research

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  22. Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study investigated whether mid-infrared...

    Authors: Emmanuel P. Mwanga, Elihaika G. Minja, Emmanuel Mrimi, Mario González Jiménez, Johnson K. Swai, Said Abbasi, Halfan S. Ngowo, Doreen J. Siria, Salum Mapua, Caleb Stica, Marta F. Maia, Ally Olotu, Maggy T. Sikulu-Lord, Francesco Baldini, Heather M. Ferguson, Klaas Wynne…

    Citation: Malaria Journal 2019 18:341

    Content type: Research

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  23. G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis. Treatment of Pla...

    Authors: Eugenia Lo, Daibin Zhong, Beka Raya, Kareen Pestana, Cristian Koepfli, Ming-Chieh Lee, Delenasaw Yewhalaw and Guiyun Yan

    Citation: Malaria Journal 2019 18:340

    Content type: Research

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  24. The recent emergence in Southeast Asia of artemisinin resistance poses major threats to malaria control and elimination globally. Green nanotechnologies can constitute interesting tools for discovering anti-ma...

    Authors: Loick P. Kojom Foko, Francois Eya’ane Meva, Carole E. Eboumbou Moukoko, Agnes A. Ntoumba, Marie I. Ngaha Njila, Philippe Belle Ebanda Kedi, Lawrence Ayong and Leopold G. Lehman

    Citation: Malaria Journal 2019 18:337

    Content type: Research

    Published on:

  25. Rapid diagnostic tests (RDTs) have been described as a source of genetic material to analyse malaria parasites in proof-of-concept studies. The increasing use of RDTs (e.g., in focal or mass screening and trea...

    Authors: The Trong Nguyen, Brice Nzigou Mombo, Albert Lalremruata, Erik Koehne, Rella Zoleko Manego, Lia Betty Dimessa Mbadinga, Ayola Akim Adegnika, Selidji Todagbe Agnandji, Bertrand Lell, Peter Gottfried Kremsner, Thirumalaisamy P Velavan, Michael Ramharter, Benjamin Mordmüller and Ghyslain Mombo-Ngoma

    Citation: Malaria Journal 2019 18:336

    Content type: Research

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  26. The decline in malaria cases and vectors is major milestone in fighting against malaria. The efficacy of MAGNet long-lasting insecticidal nets (MAGNet LLIN), an alpha-cypermethrin incorporated long-lasting net...

    Authors: Eliningaya J. Kweka, Patrick K. Tungu, Aneth M. Mahande, Humphrey D. Mazigo, Subira Sayumwe, Shandala Msangi, Lucile Lyaruu, John Waweru, William Kisinza and James Wangai

    Citation: Malaria Journal 2019 18:335

    Content type: Research

    Published on:

  27. Mosquito saliva elicits immune responses in humans following mosquito blood feeding. Detection of human antibodies recognizing the Anopheles gambiae salivary gland protein 6 (gSG6) or the gSG6-P1 peptide in resid...

    Authors: Edgar J. M. Pollard, Catriona Patterson, Tanya L. Russell, Alan Apairamo, Jance Oscar, Bruno Arcà, Chris Drakeley and Thomas R. Burkot

    Citation: Malaria Journal 2019 18:334

    Content type: Research

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  28. Malaria caused by Plasmodium falciparum parasite is still known to be one of the most significant public health problems in sub-Saharan Africa. Genetic diversity of the Sudanese P. falciparum based on the diversi...

    Authors: Nouh S. Mohamed, Musab M. Ali Albsheer, Hanadi Abdelbagi, Emanuel E. Siddig, Mona A. Mohamed, Abdallah E. Ahmed, Rihab Ali Omer, Mohamed S. Muneer, Ayman Ahmed, Hussam A. Osman, Mohamed S. Ali, Ibrahim M. Eisa and Mohamed M. Elbasheir

    Citation: Malaria Journal 2019 18:333

    Content type: Research

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  29. Misuse of long-lasting insecticidal nets together with resistance of vectors to most of the insecticides for indoor residual spraying and impregnated nets threaten malaria vector control interventions, requiri...

    Authors: Aklilu Belay, Beyene Petros, Teshome Gebre-Michael and Meshesha Balkew

    Citation: Malaria Journal 2019 18:332

    Content type: Research

    Published on:

  30. Febrile children seen in malaria hypo-endemic settings, such as the Greater Accra region (GAR) of Ghana are more likely to be suffering from a non-malarial febrile illness compared to those seen in hyper-endem...

    Authors: Harriet Affran Bonful, Adolf Kofi Awua, Martin Adjuik, Doris Tsekpetse, Richard Mawuko Kofi Adanu, Pricillia Awo Nortey, Augustine Ankomah and Kwadwo Ansah Koram

    Citation: Malaria Journal 2019 18:331

    Content type: Research

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  31. The complex life cycle of malaria parasites requires well-orchestrated stage specific gene expression. In the vertebrate host the parasites grow and multiply by schizogony in two different environments: within...

    Authors: Reto Caldelari, Sunil Dogga, Marc W. Schmid, Blandine Franke-Fayard, Chris J. Janse, Dominique Soldati-Favre and Volker Heussler

    Citation: Malaria Journal 2019 18:330

    Content type: Research

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  32. Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high even among those using the nets. Previous studies have addressed ITN owne...

    Authors: Liana R. Andronescu, Andrea G. Buchwald, Jenna E. Coalson, Lauren Cohee, Andy Bauleni, Jenny A. Walldorf, Chifundo Kandangwe, Themba Mzilahowa, Terrie E. Taylor, Don P. Mathanga and Miriam K. Laufer

    Citation: Malaria Journal 2019 18:329

    Content type: Research

    Published on:

  33. Duffy blood group antigens serve as receptors for Plasmodium vivax invasion into erythrocytes, and they are determined by polymorphisms of the Duffy antigen receptor for chemokines (DARC), also known as Fy glycop...

    Authors: Prabhanjan P. Gai, Welmoed van Loon, Konrad Siegert, Jakob Wedam, Suyamindra S. Kulkarni, Rashmi Rasalkar, Archith Boloor, Arun Kumar, Animesh Jain, Chakrapani Mahabala, Shantaram Baliga, Rajeshwari Devi, Damodara Shenoy, Pramod Gai and Frank P. Mockenhaupt

    Citation: Malaria Journal 2019 18:328

    Content type: Research

    Published on:

  34. Different antigens are needed to characterize Plasmodium falciparum infection in terms of seroreactivity and targets for invasion inhibition, in order to guide and identify the proper use of such proteins as tool...

    Authors: Jorge Bendezu, Elizabeth Villasis, Sandra Morales Ruiz, Katherine Garro, Berónica Infante, Renzo Gutierrez-Loli, Pamela Rodríguez, Manolo Fernández-Díaz, Dionicia Gamboa and Katherine Torres

    Citation: Malaria Journal 2019 18:327

    Content type: Research

    Published on:

  35. Poor knowledge on the afebrile Plasmodium falciparum biology limits elimination approaches to target asymptomatic malaria. Therefore, the association of parasite factors involved in cytoadhesion, parasite multipl...

    Authors: Himanshu Gupta, Beatriz Galatas, Gloria Matambisso, Lidia Nhamussua, Pau Cisteró, Quique Bassat, Aina Casellas, Eusébio Macete, John J. Aponte, Charfudin Sacoor, Pedro Alonso, Francisco Saúte, Caterina Guinovart, Pedro Aide and Alfredo Mayor

    Citation: Malaria Journal 2019 18:326

    Content type: Research

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  36. Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission. Artemisinin-based combination therapy (ACT) is effective ...

    Authors: André Daher, Ghait Aljayyoussi, Dhelio Pereira, Marcus V. G. Lacerda, Márcia A. A. Alexandre, Cristiana T. Nascimento, Júlio Castro Alves, Laís Bastos da Fonseca, Diego Medeiros Dias da Silva, Douglas Pereira Pinto, Danielle Fonseca Rodrigues, Ana Carolina Rios Silvino, Taís Nóbrega de Sousa, Cristiana Ferreira Alves de Brito, Feiko O. ter Kuile and David G. Lalloo

    Citation: Malaria Journal 2019 18:325

    Content type: Research

    Published on:

  37. Targeted Next Generation Sequencing (TNGS) is an efficient and economical Next Generation Sequencing (NGS) platform and the preferred choice when specific genomic regions are of interest. So far, only institut...

    Authors: Anita Ghansah, Edwin Kamau, Alfred Amambua-Ngwa, Deus S. Ishengoma, Oumou Maiga-Ascofare, Lucas Amenga-Etego, Awa Deme, William Yavo, Milijaona Randrianarivelojosia, Lynette Isabella Ochola-Oyier, Gideon Kofi Helegbe, Jeffery Bailey, Michael Alifrangis and Abdoulaye Djimde

    Citation: Malaria Journal 2019 18:324

    Content type: Meeting report

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  38. This paper outlines Zimbabwe’s potential readiness in harnessing integrated vector management (IVM) strategy for enhanced control of vector-borne diseases. The objective is to provide guidance for the country ...

    Authors: Shadreck Sande, Moses Zimba, David Nyasvisvo, Munyaradzi Mukuzunga, Emmanuel H. Kooma, Joseph Mberikunashe and Busisani Dube

    Citation: Malaria Journal 2019 18:322

    Content type: Opinion

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  39. Over the past decade, food insecurity, connected to erratic rains and reduced agricultural outputs, has plagued Malawi. Many households are turning to fishing to seek additional sources of income and food. The...

    Authors: Sara Berthe, Steven A. Harvey, Matthew Lynch, Hannah Koenker, Vincent Jumbe, Blessings Kaunda-Khangamwa and Don P. Mathanga

    Citation: Malaria Journal 2019 18:320

    Content type: Research

    Published on:

  40. Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously effective drugs has compromised anti-malarial treatment. On this basi...

    Authors: Abel O. Idowu, Wellington A. Oyibo, Sanjib Bhattacharyya, Manjeet Khubbar, Udoma E. Mendie, Violet V. Bumah, Carolyn Black, Joseph Igietseme and Anthony A. Azenabor

    Citation: Malaria Journal 2019 18:319

    Content type: Research

    Published on:

  41. Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. A cluster-randomized trial was conducted to evaluate the eff...

    Authors: Andrea M. Rehman, Catherine Maiteki-Sebuguzi, Samuel Gonahasa, Jaffer Okiring, Simon P. Kigozi, Clare I. R. Chandler, Chris Drakeley, Grant Dorsey, Moses R. Kamya and Sarah G. Staedke

    Citation: Malaria Journal 2019 18:318

    Content type: Research

    Published on:

  42. Plasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria cases. While P. vivax is identified as a major cause of severe and cerebral mala...

    Authors: Maowia M. Mukhtar, Omer A. Eisawi, Seth A. Amanfo, Elwaleed M. Elamin, Zeinab S. Imam, Faiza M. Osman and Manasik E. Hamed

    Citation: Malaria Journal 2019 18:316

    Content type: Case report

    Published on:

  43. Eave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and could constitute a scalable and low-cost supplement to current interv...

    Authors: Emmanuel P. Mwanga, Arnold S. Mmbando, Paul C. Mrosso, Caleb Stica, Salum A. Mapua, Marceline F. Finda, Khamis Kifungo, Andrew Kafwenji, April C. Monroe, Sheila B. Ogoma, Halfan S. Ngowo and Fredros O. Okumu

    Citation: Malaria Journal 2019 18:314

    Content type: Research

    Published on:

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