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  1. Malaria rapid diagnostic tests (RDTs) remain the main point-of-care tests for diagnosis of symptomatic Plasmodium falciparum malaria in endemic areas. However, parasites with gene deletions in the most common RDT...

    Authors: Ngo Duc Thang, Eduard Rovira-Vallbona, Nguyen Thi Huong Binh, Dang Viet Dung, Nguyen Thi Hong Ngoc, Tran Khanh Long, Tran Thanh Duong, Nicholas J. Martin and Kimberly A. Edgel
    Citation: Malaria Journal 2022 21:371
  2. Malaria remains the biggest public health challenge globally, and Ghana is among the 15 highest burden malaria countries in the world, with 2% of global malaria cases and 3% deaths in 2019. This study sought t...

    Authors: Seth Kwaku Afagbedzi, Yakubu Alhassan and Chris Guure
    Citation: Malaria Journal 2022 21:370
  3. Artemisinin-based combination therapy (ACT) has been recommended as the first-line treatment by the World Health Organization to treat uncomplicated Plasmodium falciparum malaria. However, the emergence and sprea...

    Authors: Xiangli Kong, Jun Feng, Yan Xu, Ge Yan and Shuisen Zhou
    Citation: Malaria Journal 2022 21:369
  4. The utilization and impact of the healthcare services depend on the perceived quality, appropriateness, ease of availability, and cost of the services. This study aimed to understand the community's perception...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Aparup Das, Vikesh Thakre, Himanshu Jayswar, Ram Shankar Sahu, Vinay K. Telasey and Altaf A. Lal
    Citation: Malaria Journal 2022 21:368
  5. Uganda conducted its third mass long-lasting insecticidal net (LLIN) distribution campaign in 2021. The target of the campaign was to ensure that 100% of households own at least one LLIN per two persons and to ac...

    Authors: Andrew Kwiringira, Carol Nanziri, Edirisa Juniour Nsubuga, Stella Martha Migamba, Vivian Ntono, Immaculate Atuhaire, Sherry Rita Ahirirwe, Alice Asio, Shaban Senyange, Petranilla Nakamya, Veronicah Masanja, Sarah Elayeete, Allan Komakech, Hildah T. Nansikombi, Patience Mwine, Rose Nampeera…
    Citation: Malaria Journal 2022 21:367
  6. Routine continuous distribution (CD) of insecticide-treated nets (ITNs) has been an important part of an overall ITN strategy to complement mass campaigns since the early 2000s. The backbone of CD implementati...

    Authors: Jane E. Miller, Kezia Malm, Aimain Alexis Serge, Marcellin Joel Ateba, Peter Gitanya, Doudou Sene, Emmanuel H. Kooma, Balla Kandeh, Lilia Gerberg and Luigi Nuñez
    Citation: Malaria Journal 2022 21:366
  7. Malaria transmission can be highly heterogeneous between and within localities, and is influenced by factors such as survival and biting frequencies of Anopheles mosquitoes. This study investigated the relationsh...

    Authors: Polius G. Pinda, Dickson S. Msaky, Letus L. Muyaga, Issa H. Mshani, Rukiyah M. Njalambaha, Japhet Kihonda, Hamis Bwanaly, Halfan S. Ngowo, Emmanuel W. Kaindoa, Lizette L. Koekemoer and Fredros O. Okumu
    Citation: Malaria Journal 2022 21:365
  8. The rate of decay of the biological efficacy of insecticides used for indoor residual spraying (IRS) is an important factor when making decisions on insecticide choice for national malaria control programmes. ...

    Authors: Delenasaw Yewhalaw, Eba Alemayehu Simma, Endalew Zemene, Kassahun Zeleke and Teshome Degefa
    Citation: Malaria Journal 2022 21:364
  9. The use of insecticide-treated bed nets has been proven to be effective in reducing malaria transmission in highly endemic areas. Use of long-lasting insecticidal nets (LLINs) has been embraced by many malaria...

    Authors: Anne Ruth Akello, John Paul Byagamy, Samuel Etajak, Charles Stephen Okadhi and Adoke Yeka
    Citation: Malaria Journal 2022 21:363
  10. Cambodia has made significant progress towards achieving malaria elimination by 2025. Cases continue to decrease and are primarily concentrated in forested areas. Forest-goers are most at risk of malaria due t...

    Authors: Sochea Phok, Kemi Tesfazghi, Andy Tompsett, Boukheng Thavrine, Po Ly, Saad El-Din Hassan, Avery Avrakotos, Jim Malster and Erica Felker-Kantor
    Citation: Malaria Journal 2022 21:362
  11. Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection of active infection with this parasite and are the o...

    Authors: Eric Rogier, Catherine Bakari, Celine I. Mandara, Mercy G. Chiduo, Mateusz Plucinski, Douglas Nace, Nastassia Battle, Franky Chacky, Susan F. Rumisha, Fabrizio Molteni, Renata Mandike, Sigsbert Mkude, Ritha Njau, Ally Mohamed, Venkatachalam Udhayakumar and Deus S. Ishengoma
    Citation: Malaria Journal 2022 21:361
  12. Pregnant women have increased susceptibility to Plasmodium falciparum malaria and acquire protective antibodies over successive pregnancies. Most studies that investigated malaria antibody responses in pregnant w...

    Authors: Meseret W. Kassa, Wina Hasang, André Barateiro, Timon Damelang, Jessica Brewster, Jamille G. Dombrowski, Rhea J. Longley, Amy W. Chung, Gerhard Wunderlich, Ivo Mueller, Elizabeth H. Aitken, Claudio R. F. Marinho and Stephen J. Rogerson
    Citation: Malaria Journal 2022 21:360
  13. Routine monitoring of anti-malarial drugs is recommended for early detection of drug resistance and to inform national malaria treatment guidelines. In Ethiopia, the national treatment guidelines employ a spec...

    Authors: Ashenafi Assefa, Hussein Mohammed, Anjoli Anand, Adugna Abera, Heven Sime, Anna A. Minta, Mekonnen Tadesse, Yehualashet Tadesse, Samuel Girma, Worku Bekele, Kebede Etana, Bereket Hailegiorgis Alemayehu, Hiwot Teka, Dereje Dilu, Mebrahtom Haile, Hiwot Solomon…
    Citation: Malaria Journal 2022 21:359
  14. Endemic malaria is present in all 15 municipalities of Roraima state, Brazilian Amazonia. Knowledge of epidemiological data of specific populations can guide health policies to formulate effective strategies f...

    Authors: Jacqueline de Aguiar Barros, Fabiana Granja, Pedro Pequeno, Paola Marchesini and Maria de Fátima Ferreira da Cruz
    Citation: Malaria Journal 2022 21:358
  15. The ability of malaria rapid diagnostic tests (RDTs) to effectively detect active infections is being compromised by the presence of malaria strains with genomic deletions at the hrp2 and hrp3 loci, encoding the ...

    Authors: Thomas C. Stabler, Ankit Dwivedi, Biraj Shrestha, Sudhaunshu Joshi, Tobias Schindler, Amed Ouattara, Guillermo A. García, Claudia Daubenberger and Joana C. Silva
    Citation: Malaria Journal 2022 21:357
  16. Immunoglobulin G (IgG) antibodies are thought to play important roles in the protection against Plasmodium falciparum (P. falciparum) malaria. A longitudinal cohort study performed in the Southern part of Benin, ...

    Authors: Abdou Khadre Dit Jadir Fall, Ikhlaq Hussain Kana, Célia Dechavanne, Asier Garcia-Senosiain, Evelyne Guitard, Jacqueline Milet, Achille Massougbodji, André Garcia, Jean-Michel Dugoujon, Florence Migot-Nabias, Michael Theisen and David Courtin
    Citation: Malaria Journal 2022 21:356
  17. Bangladesh has reduced malaria incidence and mortality by over 75% between 2010 and 2020. Widespread long-lasting insecticidal net (LLIN) distribution and use is one of the measures responsible for this succes...

    Authors: Matthew A. Aubourg, Hasan Mohammad Al-Amin, Anoop Sunkara, Sanjna Chetan, April Monroe, Ching Swe Phru, Rashidul Haque, Wasif A. Khan, Allison Hendershot, Mohammad Shafiul Alam and Neil F. Lobo
    Citation: Malaria Journal 2022 21:355
  18. This review article aims to investigate the genotypic profiles of Plasmodium falciparum and Plasmodium vivax isolates collected across a wide geographic region and their association with resistance to anti-malari...

    Authors: Farindira Vesti Rahmasari, Puji B. S. Asih, Farahana K. Dewayanti, Chawarat Rotejanaprasert, Prakaykaew Charunwatthana, Mallika Imwong and Din Syafruddin
    Citation: Malaria Journal 2022 21:354
  19. This study was designed to provide insecticide resistance data for decision-making in terms of resistance management plans in Togo.

    Authors: Yawo Apetogbo, Koffi M. Ahadji-Dabla, Dieudonné Diloma Soma, Adjovi D. Amoudji, Edoh Koffi, Kossivi I. Akagankou, Rabila Bamogo, Kelly Lionelle Ngaffo, Samina Maiga, Rachid T. Atcha‑Oubou, Ameyo M. Dorkenoo, Lucrecia Vizcaino, Audrey Lenhart, Abdoulaye Diabaté, Roch Kounbobr Dabiré and Guillaume Koffivi Ketoh
    Citation: Malaria Journal 2022 21:353
  20. Dihydroartemisinin-piperaquine (DHA-PPQ) combination therapy is the current first-line treatment for Plasmodium falciparum malaria in Thailand. Since its introduction in 2015, resistance to this drug combination ...

    Authors: Khine Nwe Win, Khajohnpong Manopwisedjaroen, Kanit Phumchuea, Chayanut Suansomjit, Kesinee Chotivanich, Saranath Lawpoolsri, Liwang Cui, Jetsumon Sattabongkot and Wang Nguitragool
    Citation: Malaria Journal 2022 21:352
  21. Declining efficacy of chloroquine against Plasmodium vivax malaria has been documented in Ethiopia. Thus, there is a need to assess the efficacy of alternative schizontocidal anti-malarials such as dihydroartemis...

    Authors: Hussein Mohammed, Heven Sime, Henok Hailgiorgis, Kale Gubae, Mebrahtom Haile, Hiwot Solomon, Kebede Etana, Samuel Girma, Worku Bekele, Melkie Chernet, Getachew Tollera, Geremew Tasew, Bokretsion Gidey, Robert J. Commons and Ashenafi Assefa
    Citation: Malaria Journal 2022 21:351
  22. Malaria is a major cause of mortality and morbidity in Uganda. Despite Uganda’s efforts to distribute bed nets, only half of households have achieved the World Health Organization (WHO) Universal Coverage Crit...

    Authors: Sae Takada, Paul J. Krezanoski, Viola Nyakato, Vincent Bátwala, A. James O’Malley, Jessica M. Perkins, Alexander C. Tsai, David R. Bangsberg, Nicholas A. Christakis and Akihiro Nishi
    Citation: Malaria Journal 2022 21:350
  23. Long-lasting insecticidal nets (LLINs) play a key role in reducing malaria transmission in endemic countries. In a previous study, the authors demonstrated a substantial decrease in the bioefficacy of LLINs fo...

    Authors: Nakei Bubun, Evodia Anetul, Melanie Koinari, Timothy W. Freeman and Stephan Karl
    Citation: Malaria Journal 2022 21:349
  24. Malaria is a priority global health disease with high morbidity and mortality especially among children under-five and pregnant women. Malaria elimination requires an effective surveillance system. The malaria...

    Authors: Peter Okpeh Amede, Chukwuma David Umeokonkwo, Susan Abege, Joseph Akawe, Jeh Derek, Elizabeth Adedire and Muhammad Shakir Balogun
    Citation: Malaria Journal 2022 21:348
  25. Malaria is an infectious disease which has been globally targeted for elimination in at least 35 of 90 endemic countries by 2030. Most successful malaria elimination country programmes have engaged the private...

    Authors: Mesele Damte Argaw, Thandisizwe Redford Mavundla, Kassa Daka Gidebo, Binyam Fekadu Desta, Heran Demissie Damte, Wondwosen Mebratu, Wasihun Edossa, Dereje Dillu, Aychiluhim Damtew Mitiku and Alebel Yaregal Desale
    Citation: Malaria Journal 2022 21:347
  26. The primary antibody (Ab) response to Plasmodium falciparum is a critical step in developing immunity to malaria. Information on the initial Ab responses of babies in malaria-endemic areas is incomplete, in part,...

    Authors: Samuel Tassi Yunga, Chathura Siriwardhana, Genevieve G. Fouda, Naveen Bobbili, Grace Sama, John J. Chen, Rose F. G. Leke and Diane Wallace Taylor
    Citation: Malaria Journal 2022 21:346
  27. Current efforts to estimate the spatially diverse malaria burden in malaria-endemic countries largely involve the use of epidemiological modelling methods for describing temporal and spatial heterogeneity usin...

    Authors: Sumaiyya G. Thawer, Monica Golumbeanu, Khalifa Munisi, Sijenunu Aaron, Frank Chacky, Samwel Lazaro, Ally Mohamed, Noela Kisoka, Christian Lengeler, Fabrizio Molteni, Amanda Ross, Robert W. Snow and Emilie Pothin
    Citation: Malaria Journal 2022 21:345
  28. Malaria burden among under-five children living in endemic areas of Yemen is largely unknown due to the lack of community-based studies. Therefore, this study determined the prevalence and risk factors associa...

    Authors: Mona A. A. Al-Quhaiti, Rashad Abdul-Ghani, Mohammed A. K. Mahdy and Methaq A. Assada
    Citation: Malaria Journal 2022 21:344
  29. The groundwork for malaria elimination does not currently consider the potential of Plasmodium zoonotic cycles that involve non-human primates (NHPs) in sylvatic environments. Since vivax malaria is less responsi...

    Authors: Bárbara Aparecida Chaves, Denise Anete Madureira de Alvarenga, Matheus de Oliveira Costa Pereira, Marcelo Gordo, Emanuelle L. Da Silva, Edson Rodrigues Costa, Aline Souza de Menezes Medeiros, Igor José Martins Pedrosa, Daniela Brito, Maurício Teixeira Lima, Maria Paula Mourão, Wuelton M. Monteiro, Nikos Vasilakis, Cristiana Ferreira Alves de Brito, Gisely C. Melo and Marcus V. G. Lacerda
    Citation: Malaria Journal 2022 21:343
  30. Inducible expression of heme oxygenase-1 (encoded by the gene HMOX1) may determine protection from heme released during malaria infections. A variable length, short tandem GT(n) repeat (STR) in HMOX1 that may inf...

    Authors: Fergus Hamilton, Ruth Mitchell, Aubrey Cunnington, Peter Ghazal and Nicholas J. Timpson
    Citation: Malaria Journal 2022 21:342
  31. Low-density malaria infections (LDMI) are defined as infections that are missed by the rapid diagnostic test (RDT) and/or microscopy which can lead to continued transmission and poses a challenge in malaria el...

    Authors: Akansha Singh, Mrigendra P. Singh, Sneha Bhandari, Harsh Rajvanshi, Sekh Nisar, Vinay Telasey, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Altaf A. Lal and Praveen K. Bharti
    Citation: Malaria Journal 2022 21:341
  32. Haemoglobinopathies and G6PD deficiency are inherited disorders found mostly in malaria-endemic areas among different tribal groups of India. However, epidemiological data specific to Particularly Vulnerable T...

    Authors: Sujata Dixit, Arundhuti Das, Ramakanta Rana, Hemant K. Khuntia, Akhil B. Ota, Sanghamitra Pati, Madhusmita Bal and Manoranjan Ranjit
    Citation: Malaria Journal 2022 21:340
  33. The Malaria Vaccine Implementation Programme (MVIP) coordinates the routine implementation of the RTS,S vaccine pilot in strategically selected locations in Malawi, Kenya, and Ghana. The pilot programme thorou...

    Authors: Dominic Yeboah, Joseph Owusu-Marfo and Yaa Nyarko Agyeman
    Citation: Malaria Journal 2022 21:339
  34. Globally, malaria is among the leading cause of under-five mortality and morbidity. Despite various malaria elimination strategies being implemented in the last decades, malaria remains a major public health c...

    Authors: Gebeyaw Biset, Abay Woday Tadess, Kirubel Dagnaw Tegegne, Lehulu Tilahun and Natnael Atnafu
    Citation: Malaria Journal 2022 21:338
  35. Accurate detection of asymptomatic malaria parasitaemia in children living in high transmission areas is important for malaria control and reduction programmes that employ screen-and-treat surveillance strateg...

    Authors: Lindsey B. Turnbull, George Ayodo, Veronicah Knight, Chandy C. John, Megan S. McHenry and Tuan M. Tran
    Citation: Malaria Journal 2022 21:337
  36. Eotaxin-1 concentrations in plasma have been inversely associated with malaria exposure, malaria infection and pregnancy, but the effect of these conditions on the levels of the related chemokines eotaxin-2 an...

    Authors: Cristina Mancebo-Pérez, Marta Vidal, Ruth Aguilar, Diana Barrios, Azucena Bardají, Maria Ome-Kaius, Clara Menéndez, Stephen J. Rogerson, Carlota Dobaño, Gemma Moncunill and Pilar Requena
    Citation: Malaria Journal 2022 21:336
  37. Malaria remains a serious health problem in the southern border provinces of Thailand. The issue areas can be identified using an appropriate statistical model. This study aimed to investigate malaria for its ...

    Authors: Lumpoo Ammatawiyanon, Phattrawan Tongkumchum, Apiradee Lim and Don McNeil
    Citation: Malaria Journal 2022 21:334
  38. To understand how Plasmodium falciparum malaria is controlled, it is essential to elucidate the transcriptomic responses of the human host in naturally-exposed populations. Various individual studies of the human...

    Authors: Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi and Li-hua Xie
    Citation: Malaria Journal 2022 21:333
  39. Despite several efforts at addressing the barriers to adherence to the WHO-supported test, treat and track (T3) malaria case management guideline in Ghana, adherence remains a challenge. This study explored th...

    Authors: Augusta Soninour Kolekang, Yaw Afrane, Stephen Apanga, Dejan Zurovac, Anthony Kwarteng, Samuel Afari-Asiedu, Kwaku Poku Asante and Anthony Danso-Appiah
    Citation: Malaria Journal 2022 21:332
  40. Gametocytes are the sexual stages ensuring continuity of the development cycle of the parasite, as well as its transmission to humans. The efficacy of artemisinin-based anti-malarials against asexual stages of Pl...

    Authors: Malalanandrianina A. Rakotoarisoa, Jocia Fenomanana, Bronislaw Tchesterico Dodoson, Voahangy Hanitriniaina I. Andrianaranjaka and Arsène Ratsimbasoa
    Citation: Malaria Journal 2022 21:331
  41. In 2017, several new housing districts were constructed on Bioko Island, Equatorial Guinea. This case study assessed the impact construction projects had on mosquito larval habitats and the effectiveness of la...

    Authors: Guillermo A. García, Godwin Fuseini, Olivier Tresor Donfack, Rachel N. Wofford, Jose Antonio Mba Nlang, Prudencio Bibang Efiri, Valeriano Oluy Nsue Maye, Thomas A. Weppelmann, David Galick, Wonder Philip Phiri, Kylie DeBoer, Jordan M. Smith, Jeremias Nzamio Mba Eyono, Matilde Riloha Rivas, Carlos A. Guerra and Michael E. von Fricken
    Citation: Malaria Journal 2022 21:328
  42. Kalimantan is a part of Indonesia, which occupies the southern three-quarters of the island of Borneo, sharing a border with the Malaysian states of Sabah and Sarawak. Although most areas of Kalimantan have lo...

    Authors: Sri Riyati Sugiarto, J. Kevin Baird, Balbir Singh, Iqbal Elyazar and Timothy M. E. Davis
    Citation: Malaria Journal 2022 21:327
  43. Asymptomatic carriage of malaria parasites is common in high transmission intensity areas and confounds clinical case definitions for research studies. This is important for investigations that aim to identify...

    Authors: Kennedy Mwai, Irene Nkumama, Amos Thairu, James Mburu, Dennis Odera, Rinter Kimathi, Lydia Nyamako, James Tuju, Samson Kinyanjui, Eustasius Musenge and Faith Osier
    Citation: Malaria Journal 2022 21:326
  44. Seasonal patterns of malaria cases in many parts of Africa are generally associated with rainfall, yet in the dry seasons, malaria transmission declines but does not always cease. It is important to understand...

    Authors: Carolina Duque, Mukuma Lubinda, Japhet Matoba, Caison Sing’anga, Jennifer Stevenson, Timothy Shields and Clive J. Shiff
    Citation: Malaria Journal 2022 21:325
  45. Broflanilide is a newly discovered insecticide with a novel mode of action targeting insect γ-aminobutyric acid receptors. The efficacy of VECTRON T500, a wettable powder formulation of broflanilide, was assesse...

    Authors: Renaud Govoetchan, Augustin Fongnikin, Thomas Syme, Graham Small, Martial Gbegbo, Damien Todjinou, Mark Rowland, Derric Nimmo, Germain Gil Padonou and Corine Ngufor
    Citation: Malaria Journal 2022 21:324
  46. Human mobility behaviour modelling plays an essential role in the understanding and control of the spread of contagious diseases by limiting the contact among individuals, predicting the spatio-temporal evolut...

    Authors: Werissaw Haileselassie, Ashagrie Getnet, Hiwot Solomon, Wakgari Deressa, Guiyun Yan and Daniel M. Parker
    Citation: Malaria Journal 2022 21:323
  47. For children below 6 years with suspected severe malaria attending a health care provider unable to provide parenteral malaria treatment, pre-referral rectal artesunate (RAS) is recommended by the World Health...

    Authors: Phyllis Awor, Joseph Kimera, Proscovia Athieno, Gloria Tumukunde, Jean Okitawutshu, Antoinette Tshefu, Elizabeth Omoluabi, Aita Signorell, Nina Brunner, Jean-Claude Kalenga, Babatunde Akano, Kazeem Ayodeji, Charles Okon, Ocheche Yusuf, Giulia Delvento, Tristan Lee…
    Citation: Malaria Journal 2022 21:322

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