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  1. Content type: Research

    Glucose-6-phosphate dehydrogenase deficiency (G6PDd), haemoglobin C (HbC) and S (HbS) are inherited blood disorders (IBD) common in populations in malaria endemic areas. All are associated to some degree with ...

    Authors: Lynn Grignard, Catherine Mair, Jonathan Curry, Laleta Mahey, Guide J. H. Bastiaens, Alfred B. Tiono, Joseph Okebe, Sam A. Coulibaly, Bronner P. Gonçalves, Muna Affara, Alphonse Ouédraogo, Edith C. Bougouma, Guillaume S. Sanou, Issa Nébié, Kjerstin H. W. Lanke, Sodiomon B. Sirima…

    Citation: Malaria Journal 2019 18:14

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  2. Content type: Research

    Prior to this project, only a handful of online visualizations existed for exploring the published literature on molecular markers of antimalarial drug resistance, and none specifically for the markers associa...

    Authors: Sabina Dahlström Otienoburu, Ignacio Suay, Steven Garcia, Nigel V. Thomas, Suttipat Srisutham, Anders Björkman and Georgina S. Humphreys

    Citation: Malaria Journal 2019 18:12

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  3. Content type: Research

    A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 anti...

    Authors: Andrea A. Berry, Eric R. Gottlieb, Bourema Kouriba, Issa Diarra, Mahamadou A. Thera, Sheetij Dutta, Drissa Coulibaly, Amed Ouattara, Amadou Niangaly, Abdoulaye K. Kone, Karim Traore, Youssouf Tolo, Vladimir Mishcherkin, Lorraine Soisson, Carter L. Diggs, William C. Blackwelder…

    Citation: Malaria Journal 2019 18:13

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  4. Content type: Research

    Antibodies targeting malaria blood-stage antigens are important targets of naturally acquired immunity, and may act as valuable biomarkers of malaria exposure.

    Authors: Priyanka Barua, James G. Beeson, Kenneth Maleta, Per Ashorn and Stephen J. Rogerson

    Citation: Malaria Journal 2019 18:11

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  5. Content type: Research

    Reduced artemisinin susceptibility and artemisinin-based combination therapy (ACT)-resistance against Plasmodium falciparum and chloroquine (CQ)-resistant P. vivax malaria has been reported in Vietnam. Two therap...

    Authors: Nguyen Chinh Phong, Marina Chavchich, Huynh Hong Quang, Nguyen Ngoc San, Geoffrey W. Birrell, Ilin Chuang, Nicholas J. Martin, Nguyen Duc Manh and Michael D. Edstein

    Citation: Malaria Journal 2019 18:10

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  6. Content type: Research

    Malaria can be transmitted by blood transfusion from human to human and it is responsible for the majority of transfusion-transmitted infectious diseases worldwide. In sub-Saharan Africa, it had been estimated...

    Authors: Tobias Schindler, Tamy Robaina, Julian Sax, Jose Raso Bieri, Maximilian Mpina, Linda Gondwe, Ludmila Acuche, Guillermo Garcia, Carlos Cortes, Carl Maas and Claudia Daubenberger

    Citation: Malaria Journal 2019 18:9

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  7. Content type: Methodology

    The erythrocytic stage of Plasmodium falciparum parasites in humans is clinically important, as the parasites at this growth stage causes malarial symptoms. Most of the currently available anti-malarial drugs tar...

    Authors: Takahiro Tougan, Yuji Toya, Kinya Uchihashi and Toshihiro Horii

    Citation: Malaria Journal 2019 18:8

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  8. Content type: Research

    Plasmodium falciparum infection during pregnancy is a major cause of poor maternal health, adverse foetal outcome and infant mortality in sub-Saharan Africa. Genetic disposition is involved in susceptibility to m...

    Authors: Welmoed van Loon, Prabhanjan P. Gai, Lutz Hamann, George Bedu-Addo and Frank P. Mockenhaupt

    Citation: Malaria Journal 2019 18:7

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  9. Content type: Review

    Malaria cases and deaths decreased dramatically in recent years, largely due to effective vector control interventions. Persistence of transmission after good coverage has been achieved with high-quality vecto...

    Authors: April Monroe, Sarah Moore, Hannah Koenker, Matthew Lynch and Emily Ricotta

    Citation: Malaria Journal 2019 18:6

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  10. Content type: Methodology

    Global efforts to address the burden of malaria have stagnated in recent years with malaria cases beginning to rise. Substandard and falsified anti-malarial treatments contribute to this stagnation. Poor quali...

    Authors: Sachiko Ozawa, Daniel R. Evans, Colleen R. Higgins, Sarah K. Laing and Phyllis Awor

    Citation: Malaria Journal 2019 18:5

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  11. Content type: Research

    Emerging resistance to anti-malarial drugs has led malaria researchers to investigate what covariates (parasite and host factors) are associated with resistance. In this regard, investigation of how covariates...

    Authors: Saeed Sharifi-Malvajerdi, Feiyu Zhu, Colin B. Fogarty, Michael P. Fay, Rick M. Fairhurst, Jennifer A. Flegg, Kasia Stepniewska and Dylan S. Small

    Citation: Malaria Journal 2019 18:4

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  12. Content type: Research

    There has been significant progress in eliminating malaria in Iran. The aim of this study is to investigate the structure of inter-organizational collaboration networks in the field of unauthorized immigrants ...

    Authors: Ensiyeh Jamshidi, Hassan Eftekhar Ardebili, Reza Yousefi-Nooraie, Ahmad Raeisi, Hossein Malekafzali Ardakani, Roya Sadeghi, Ahmad Ali Hanafi-Bojd and Reza Majdzadeh

    Citation: Malaria Journal 2019 18:1

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  13. Content type: Research

    Saglin, a 100 kDa protein composed of two 50 kDa homodimers, is present in the salivary glands of Anopheles gambiae and has been considered an essential receptor for sporozoites (SPZ) of Plasmodium berghei and Pl...

    Authors: David A. O’Brochta, Robert Alford, Robert Harrell, Channa Aluvihare, Abraham G. Eappen, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman and Peter F. Billingsley

    Citation: Malaria Journal 2019 18:2

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  14. Content type: Research

    Nationally-representative household surveys are the standard approach to monitor access to and treatment with artemisinin-based combination therapy (ACT) among children under 5 years (U5), however these indica...

    Authors: Ruth A. Ashton, Bakary Doumbia, Diadier Diallo, Thomas Druetz, Lia Florey, Cameron Taylor, Fred Arnold, Jules Mihigo, Diakalia Koné, Seydou Fomba, Erin Eckert and Thomas P. Eisele

    Citation: Malaria Journal 2019 18:3

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  15. Content type: Research

    In recognition of the threat of insecticide resistance in vectors of malaria, the WHO Global Malaria Programme recommends the development of an appropriate and comprehensive response to insecticide resistance....

    Authors: Fiacre R. Agossa, Gil G. Padonou, Arsene Jacques Y. H. Fassinou, Esdras M. Odjo, Osei K. Akuoko, Albert Salako, Zinsou C. Koukpo, Udoka C. Nwangwu, Bruno Akinro, Michel Sezonlin and Martin C. Akogbeto

    Citation: Malaria Journal 2018 17:484

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  16. Content type: Research

    The emergence and transnational spread of artemisinin resistance in Plasmodium falciparum in the Greater Mekong Sub-region (GMS) is a serious threat to malaria elimination in the region and could present a threat...

    Authors: Moritoshi Iwagami, Masami Nakatsu, Phonepadith Khattignavong, Pheovaly Soundala, Sengdeuane Keomalaphet, Lavy Lorpachan, Phonepadith Xangsayalath, Emilie Matsumoto-Takahashi, Virginie Pommelet, Bouasy Hongvanthong, Paul T. Brey and Shigeyuki Kano

    Citation: Malaria Journal 2018 17:483

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  17. Content type: Research

    Mobile health (mHealth), which uses technology such as mobile phones to improve patient health and health care delivery, is increasingly being tested as an intervention to promote health worker (HW) performanc...

    Authors: Blessings N. Kaunda-Khangamwa, Laura C. Steinhardt, Alexander K. Rowe, Austin Gumbo, Dubulao Moyo, Humphreys Nsona, Peter Troell, Dejan Zurovac and Don Mathanga

    Citation: Malaria Journal 2018 17:481

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  18. Content type: Research

    Subpatent malaria infections, or low-density infections below the detection threshold of microscopy or standard rapid diagnostic testing (RDT), can perpetuate persistent transmission and, therefore, may be a b...

    Authors: Patrick McCreesh, Davis Mumbengegwi, Kathryn Roberts, Munyaradzi Tambo, Jennifer Smith, Brooke Whittemore, Gerard Kelly, Caitlin Moe, Max Murphy, Mukosha Chisenga, Bryan Greenhouse, Henry Ntuku, Immo Kleinschmidt, Hugh Sturrock, Petrina Uusiku, Roland Gosling…

    Citation: Malaria Journal 2018 17:480

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  19. Content type: Research

    Plasmodium falciparum has shown multidrug resistance, leading to the necessity for the development of new drugs with novel targets, such as the synthesis of isoprenic precursors, which are excellent targets becau...

    Authors: Valeska S. de Sena Pereira, Flávio da Silva Emery, Lis Lobo, Fátima Nogueira, Jonas I. N. Oliveira, Umberto L. Fulco, Eudenilson L. Albuquerque, Alejandro M. Katzin and Valter F. de Andrade-Neto

    Citation: Malaria Journal 2018 17:482

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  20. Content type: Research

    Gaps remain in understanding the role of caregiver responses on time to seek appropriate care. The objective of this study was to describe caregiver responses to illness and the impact of these responses on ti...

    Authors: Arthur Mpimbaza, Anne Katahoire, Philip J. Rosenthal, Charles Karamagi and Grace Ndeezi

    Citation: Malaria Journal 2018 17:476

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  21. Content type: Research

    The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates of chloroquine-resistant molecular markers (Plasmodium falciparum c...

    Authors: Ying Dong, Jian Wang, Aiming Sun, Yan Deng, Mengni Chen, Yanchun Xu and Jingpo Xue

    Citation: Malaria Journal 2018 17:478

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  22. Content type: Research

    The proportion of mosquito blood-meals that are of human origin, referred to as the ‘human blood index’ or HBI, is a key determinant of malaria transmission.

    Authors: James Orsborne, Luis Furuya-Kanamori, Claire L. Jeffries, Mojca Kristan, Abdul Rahim Mohammed, Yaw A. Afrane, Kathleen O’Reilly, Eduardo Massad, Chris Drakeley, Thomas Walker and Laith Yakob

    Citation: Malaria Journal 2018 17:479

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  23. Content type: Research

    Acute kidney injury (AKI) is a common complication of malaria. In low resource settings, a lack of diagnostic tools and delayed treatment of malaria associated AKI lead to significant morbidity and mortality. ...

    Authors: Viviane Calice-Silva, Euclides Sacomboio, Jochen G. Raimann, Rhys Evans, Cruz dos Santos Sebastião, Adelino Tchilanda Tchivango, Peter Kotanko, Nathan Levin and Roberto Pecoits-Filho

    Citation: Malaria Journal 2018 17:477

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  24. Content type: Research

    Antibodies against the merozoite surface protein 1-19 (MSP1-19) and the apical membrane antigen 1 (AMA1) of the malaria parasite (Plasmodium vivax) are proven to be important in protection against clinical diseas...

    Authors: Rajika L. Dewasurendra, Anna Jeffreys, Sharmini A. Gunawardena, Naduviladath V. Chandrasekharan, Kirk Rockett, Dominic Kwiatkowski and Nadira D. Karunaweera

    Citation: Malaria Journal 2018 17:473

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  25. Content type: Research

    There is growing interest to add mass drug administration (MDA) to the already existing malaria prevention strategies, such as indoor residual spraying (IRS). However, successful MDA and IRS requires high popu...

    Authors: Humphrey Wanzira, Susan Naiga, Ronald Mulebeke, Fred Bukenya, Mariam Nabukenya, Osborn Omoding, Dorothy Echodu and Adoke Yeka

    Citation: Malaria Journal 2018 17:474

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  26. Content type: Research

    While malaria incidence in Indonesia has decreased threefold in the last decade, more than 200,000 cases were reported in 2016. Different endemicity of Plasmodium falciparum malaria among several islands in Indon...

    Authors: Sukmawati Basuki, Fitriah, Petronella M. Risamasu, Kasmijati, Pancawati Ariami, Sugeng Riyanto, Ari Hidayat, Dewi Susilowati, Iskandar, Budi Armika, Budiono, Yoes P. Dachlan, Hiroji Kanbara and Haruki Uemura

    Citation: Malaria Journal 2018 17:475

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  27. Content type: Research

    In Pakistan, artesunate (AS) in combination with sulfadoxine–pyrimethamine (SP) is the recommended treatment for uncomplicated Plasmodium falciparum malaria. Monitoring molecular markers of anti-malarial drug res...

    Authors: Adnan Yaqoob, Aamer Ali Khattak, Muhammad Faisal Nadeem, Huma Fatima, Gillian Mbambo, Amed Ouattara, Matthew Adams, Nadia Zeeshan and Shannon Takala-Harrison

    Citation: Malaria Journal 2018 17:471

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  28. Content type: Research

    Plasmodium falciparum malaria remains a major health challenge in Nigeria despite the global decline of its incidence and mortality rates. Although significant progress has been made in preventing the transmissio...

    Authors: Bolajoko E. Bankole, Adeyemi T. Kayode, Iguosadolo O. Nosamiefan, Philomena Eromon, Mary L. Baniecki, Rachel F. Daniels, Elizabeth J. Hamilton, Katelyn Durfee, Bronwyn MacInnis, Henrietta Okafor, Akintunde Sowunmi, Sarah K. Volkman, Pardis Sabeti, Dyann Wirth, Christian T. Happi and Onikepe A. Folarin

    Citation: Malaria Journal 2018 17:472

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  29. Content type: Research

    This study seeks to compare the performance of HRP2 (First Response) and pLDH/HRP2 (Combo) RDTs for falciparum malaria against microscopy and PCR in acutely ill febrile children at presentation and follow-up.

    Authors: Isabella A. Quakyi, George O. Adjei, David J. Sullivan Jr., Amos Laar, Judith K. Stephens, Richmond Owusu, Peter Winch, Kwame S. Sakyi, Nathaniel Coleman, Francis D. Krampa, Edward Essuman, Vivian N. A. Aubyn, Isaac A. Boateng, Bernard B. Borteih, Linda Vanotoo, Juliet Tuakli…

    Citation: Malaria Journal 2018 17:468

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  30. Content type: Case report

    Congenital malaria is usually defined as the detection of asexual forms of Plasmodium spp. in a blood sample of a neonate during perinatal age if there is no possibility of postpartum infection by a mosquito bite...

    Authors: Lorenza Romani, Stefania Pane, Carlo Severini, Michela Menegon, Gianluca Foglietta, Stefania Bernardi, Hyppolite K. Tchidjou, Andrea Onetti Muda, Paolo Palma and Lorenza Putignani

    Citation: Malaria Journal 2018 17:470

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  31. Content type: Opinion

    According to the World Health Organization (WHO), Plasmodium falciparum malaria during pregnancy is responsible for deleterious consequences for the mother and her child. The administration of intermittent preven...

    Authors: Tiphaine Gaillard, Manon Boxberger, Marylin Madamet and Bruno Pradines

    Citation: Malaria Journal 2018 17:469

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  32. Content type: Research

    For the success of the malaria control and eradication programme it is essential to reduce parasite transmission by mosquito vectors. In the midguts of mosquitoes fed with parasite-infected blood, sexual-stage...

    Authors: Rachaneeporn Jenwithisuk, Niwat Kangwanrangsan, Mayumi Tachibana, Amporn Thongkukiatkul, Hitoshi Otsuki, Jetsumon Sattabongkot, Takafumi Tsuboi, Motomi Torii and Tomoko Ishino

    Citation: Malaria Journal 2018 17:466

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  33. Content type: Research

    Evolutionary pressure by Plasmodium falciparum malaria is known to have favoured a large number of human gene adaptations, but there is surprisingly little investigation of the effect of malaria on human mitochon...

    Authors: Casey Fowler, Christine Cserti-Gazdewich, Aggrey Dhabangi, Charles Musoke, Himanshu Sharma, Sami S. Amr and Walter Dzik

    Citation: Malaria Journal 2018 17:467

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  34. Content type: Research

    The continued spectre of resistance to existing anti-malarials necessitates the pursuit of novel targets and mechanisms of action for drug development. One class of promising targets consists of the 80S riboso...

    Authors: Christine Moore Sheridan, Valentina E. Garcia, Vida Ahyong and Joseph L. DeRisi

    Citation: Malaria Journal 2018 17:465

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  35. Content type: Research

    Most epidemiological studies on the interplay between iron deficiency and malaria risk classify individuals as iron-deficient or iron-replete based on inflammation-dependent iron markers and adjustment for inf...

    Authors: Filip C. Castberg, Edem W. Sarbah, Kwadwo A. Koram, Nicholas Opoku, Michael F. Ofori, Bjarne Styrishave, Lars Hviid and Jørgen A. L. Kurtzhals

    Citation: Malaria Journal 2018 17:464

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  36. Content type: Review

    Reaching the overall goal of eliminating malaria requires halting disease transmission. One approach to blocking transmission is to prevent passage of the parasite to a mosquito, by preventing formation or tra...

    Authors: Jeremy Burrows, Hannah Slater, Fiona Macintyre, Sarah Rees, Anna Thomas, Fredros Okumu, Rob Hooft van Huijsduijnen, Stephan Duparc and Timothy N. C. Wells

    Citation: Malaria Journal 2018 17:462

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  37. Content type: Research

    Spreading Plasmodium falciparum artemisinin drug resistance threatens global malaria public health gains. Limited data exist to define the extent of P. falciparum artemisinin resistance southeast of the Greater M...

    Authors: Matthew J. Grigg, Timothy William, Kim A. Piera, Giri S. Rajahram, Jenarun Jelip, Ammar Aziz, Jayaram Menon, Jutta Marfurt, Ric N. Price, Sarah Auburn, Bridget E. Barber, Tsin W. Yeo and Nicholas M. Anstey

    Citation: Malaria Journal 2018 17:463

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  38. Content type: Research

    In malaria endemic countries, asymptomatic cases constitute an important reservoir of infections sustaining transmission. Estimating the burden of the asymptomatic population and identifying areas with elevate...

    Authors: Mady Ouédraogo, Sékou Samadoulougou, Toussaint Rouamba, Hervé Hien, John E. M. Sawadogo, Halidou Tinto, Victor A. Alegana, Niko Speybroeck and Fati Kirakoya-Samadoulougou

    Citation: Malaria Journal 2018 17:460

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  39. Content type: Research

    In Tanzania, the roles of men and women are classified based on the local cultural context. While men are usually the breadwinners, women are traditionally responsible for most domestic chores. Particularly fo...

    Authors: Angel Dillip, Zawadi Mageni Mboma, George Greer and Lena M. Lorenz

    Citation: Malaria Journal 2018 17:459

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  40. Content type: Research

    Ensuring malaria commodity availability at health facilities is a cornerstone of malaria control. Since 2013, the Guinea National Malaria Control Programme has been routinely collecting data on stock levels of...

    Authors: Yu Sun, Timothée Guilavogui, Alioune Camara, Mohamed Dioubaté, Babacar Deen Toure, Claude Bahati, Marie Paule Fargier, Jessica Butts, Patrick Condo, Abdoulaye Sarr and Mateusz M. Plucinski

    Citation: Malaria Journal 2018 17:461

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  41. Content type: Research

    Malaria is still a serious public health problem on Bioko Island (Equatorial Guinea), although the number of annual cases has been greatly reduced since 2004 through the Bioko Island Malaria Control Project (B...

    Authors: Jiang-Tao Chen, Jian Li, Guang-Cai Zha, Guang Huang, Zhi-Xiu Huang, Dong-De Xie, Xia Zhou, Huan-Tong Mo, Juan Urbano Monsuy Eyi, Rocio Apicante Matesa, Maximo Miko Ondo Obono, Shan Li, Xiang-Zhi Liu and Min Lin

    Citation: Malaria Journal 2018 17:458

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  42. Content type: Research

    Malaria is still a major public health concern in Bangladesh in spite of mass distribution of long-lasting insecticide-treated nets (LLINs) as a key preventive strategy. There might be a considerable gap betwe...

    Authors: Fouzia Khanam, Md Belal Hossain, Tridib Roy Chowdhury, Md Sajedur Rahman, Moktadir Kabir, Shamsun Naher, Md Akramul Islam and Mahfuzar Rahman

    Citation: Malaria Journal 2018 17:455

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  43. Content type: Methodology

    The malaria Eradication Research Agenda (malERA) has identified human-to-mosquito transmission of Plasmodium falciparum as a major target for eradication. The cornerstone for identifying and evaluating transmissi...

    Authors: Ashutosh K. Pathak, Justine C. Shiau, Matthew B. Thomas and Courtney C. Murdock

    Citation: Malaria Journal 2018 17:457

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  44. Content type: Research

    Plasmodium falciparum haemozoin, a detoxification product of digested haemoglobin from infected erythrocytes, is released into the bloodstream upon schizont rupture and accumulates in leukocytes. High levels of h...

    Authors: Yolanda Corbett, Sarah D’Alessandro, Silvia Parapini, Diletta Scaccabarozzi, Parisa Kalantari, Stefania Zava, Flavio Giavarini, Donatella Caruso, Irma Colombo, Timothy J. Egan and Nicoletta Basilico

    Citation: Malaria Journal 2018 17:456

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  45. Content type: Review

    The core vector control measures, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), reduce the risk of malaria infection by targeting indoor biting mosquitoes. These two interventions ...

    Authors: Taye Gari and Bernt Lindtjørn

    Citation: Malaria Journal 2018 17:454

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  46. Content type: Research

    A nationwide, school, malaria survey was implemented to assess the risk factors of malaria prevalence and bed net use among primary school children in mainland Tanzania. This allowed the mapping of malaria pre...

    Authors: Frank Chacky, Manuela Runge, Susan F. Rumisha, Pendael Machafuko, Prosper Chaki, Julius J. Massaga, Ally Mohamed, Emilie Pothin, Fabrizio Molteni, Robert W. Snow, Christian Lengeler and Renata Mandike

    Citation: Malaria Journal 2018 17:452

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  47. Content type: Research

    In Ethiopia, medicinal plants have been used to treat different diseases, including malaria, for many centuries. People living in rural areas are especially noted for their use of medicinal plants as a major c...

    Authors: Abyot Endale Gurmu, Teresa Kisi, Habteweld Shibru, Bertrand Graz and Merlin Willcox

    Citation: Malaria Journal 2018 17:451

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  48. Content type: Research

    Plasmodium falciparum infected erythrocytes sequestering in placental tissue release Plasmodium lactate dehydrogenase (pLDH) and histidine-rich protein-II (HRP-II). These proteins can be detected in peripheral bl...

    Authors: Rosette Megnekou, Jean Claude Djontu, Benderli C. Nana, Jude D. Bigoga, Maurice Fotso, Balotin Fogang and Rose F. G. Leke

    Citation: Malaria Journal 2018 17:450

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  49. Content type: Case report

    Plasmodium knowlesi, a malaria parasite typically found in long-tailed and pig-tailed macaques, is the most common cause of human malaria in Malaysian Borneo. Infections in humans result in a spectrum of disease,...

    Authors: Chee Yik Chang, Wei Chieng Pui, Khamisah Abdul Kadir and Balbir Singh

    Citation: Malaria Journal 2018 17:448

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