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  1. Research

    Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

    Malaria, HIV/AIDS, and tuberculosis endemic areas show considerable geographical overlap, leading to incidence of co-infections. This requires treatment with multiple drugs, potentially causing adverse drug–dr...

    Maarten van der Velden, Albert Bilos, Jeroen J. M. W. van den Heuvel, Sanna R. Rijpma, Evelien G. E. Hurkmans, Robert W. Sauerwein, Frans G. M. Russel and Jan B. Koenderink

    Malaria Journal 2017 16:422

    Published on: 23 October 2017

  2. Research

    A systematic review and synthesis of the strengths and limitations of measuring malaria mortality through verbal autopsy

    Lack of valid and reliable data on malaria deaths continues to be a problem that plagues the global health community. To address this gap, the verbal autopsy (VA) method was developed to ascertain cause of dea...

    Samantha Herrera, Yeetey Enuameh, George Adjei, Kenneth Ayuurebobi Ae-Ngibise, Kwaku Poku Asante, Osman Sankoh, Seth Owusu-Agyei and Yazoume Yé

    Malaria Journal 2017 16:421

    Published on: 23 October 2017

  3. Research

    Integrated community case management by drug sellers influences appropriate treatment of paediatric febrile illness in South Western Uganda: a quasi-experimental study

    Fever case management is a major challenge for improved child health globally, despite existence of cheap and effective child survival health technologies. The integrated Community Case Management (iCCM) inter...

    Freddy Eric Kitutu, Joan Nakayaga Kalyango, Chrispus Mayora, Katarina Ekholm Selling, Stefan Peterson and Henry Wamani

    Malaria Journal 2017 16:425

    Published on: 23 October 2017

  4. Research

    The underlying reasons for very high levels of bed net use, and higher malaria infection prevalence among bed net users than non-users in the Tanzanian city of Dar es Salaam: a qualitative study

    Bed nets reduce malaria-related illness and deaths, by forming a protective barrier around people sleeping under them. When impregnated with long-lasting insecticide formulations they also repel or kill mosqui...

    Daniel Msellemu, Aloysia Shemdoe, Christina Makungu, Yeromini Mlacha, Khadija Kannady, Stefan Dongus, Gerry F. Killeen and Angel Dillip

    Malaria Journal 2017 16:423

    Published on: 23 October 2017

  5. Research

    Factors associated with population coverage of targeted malaria elimination (TME) in southern Savannakhet Province, Lao PDR

    Targeted malaria elimination (TME) in Lao PDR (Laos) included three rounds of mass drug administrations (MDA) against malaria followed by quarterly blood surveys in two villages in Nong District at Savannakhet...

    Bipin Adhikari, Koukeo Phommasone, Tiengkham Pongvongsa, Palingnaphone Kommarasy, Xayaphone Soundala, Gisela Henriques, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Lorenz von Seidlein, Phaik Yeong Cheah, Christopher Pell and Mayfong Mayxay

    Malaria Journal 2017 16:424

    Published on: 23 October 2017

  6. Research

    Temporal dynamic of malaria in a suburban area along the Niger River

    Even if rainfall and temperature are factors classically associated to malaria, little is known about other meteorological factors, their variability and combinations related to malaria, in association with ri...

    Mahamadou Soumana Sissoko, Kourane Sissoko, Bourama Kamate, Yacouba Samake, Siaka Goita, Abdoulaye Dabo, Mama Yena, Nadine Dessay, Renaud Piarroux, Ogobara K. Doumbo and Jean Gaudart

    Malaria Journal 2017 16:420

    Published on: 23 October 2017

  7. Research

    Diagnostic performance of the loop-mediated isothermal amplification (LAMP) based illumigene® malaria assay in a non-endemic region

    Light microscopy and antigen-based rapid diagnostic tests are the primary diagnostic tools for detecting malaria, although being labour-intensive and frequently challenged by lack of personnel’s experience and...

    Anne-Sophie De Koninck, Lieselotte Cnops, Mattias Hofmans, Jan Jacobs, Dorien Van den Bossche and Jan Philippé

    Malaria Journal 2017 16:418

    Published on: 17 October 2017

  8. Research

    Absence of Plasmodium inui and Plasmodium cynomolgi, but detection of Plasmodium knowlesi and Plasmodium vivax infections in asymptomatic humans in the Betong division of Sarawak, Malaysian Borneo

    Plasmodium knowlesi, a simian malaria parasite, has become the main cause of malaria in Sarawak, Malaysian Borneo. Epidemiological data on malaria for Sarawak has been derived solely f...

    Angela Siner, Sze-Tze Liew, Khamisah Abdul Kadir, Dayang Shuaisah Awang Mohamad, Felicia Kavita Thomas, Mohammad Zulkarnaen and Balbir Singh

    Malaria Journal 2017 16:417

    Published on: 17 October 2017

  9. Research

    Malaria risk factors and care-seeking behaviour within the private sector among high-risk populations in Vietnam: a qualitative study

    Vietnam has successfully reduced malaria incidence by more than 90% over the past 10 years, and is now preparing for malaria elimination. However, the remaining malaria burden resides in individuals that are h...

    Ingrid Chen, Huong Ngo Thi Thanh, Andrew Lover, Phung Thi Thao, Tang Viet Luu, Hoang Nghia Thang, Ngo Duc Thang, Josselyn Neukom and Adam Bennett

    Malaria Journal 2017 16:414

    Published on: 16 October 2017

  10. Research

    High prevalence of very-low Plasmodium falciparum and Plasmodium vivax parasitaemia carriers in the Peruvian Amazon: insights into local and occupational mobility-related transmission

    The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years. This study tested the hypothesis that the maintenance and emergence of malaria...

    Gabriel Carrasco-Escobar, Julio Miranda-Alban, Carlos Fernandez-Miñope, Kimberly C. Brouwer, Katherine Torres, Maritza Calderon, Dionicia Gamboa, Alejandro Llanos-Cuentas and Joseph M. Vinetz

    Malaria Journal 2017 16:415

    Published on: 16 October 2017

  11. Research

    Molecular surveillance of pfhrp2 and pfhrp3 deletions in Plasmodium falciparum isolates from Mozambique

    Malaria programmes use Plasmodium falciparum histidine-rich protein-2 (PfHRP2) based rapid diagnostic tests (RDTs) for malaria diagnosis. The deletion of this target antigen could potentially lead to misdiagnosis...

    Himanshu Gupta, Gloria Matambisso, Beatriz Galatas, Pau Cisteró, Lidia Nhamussua, Wilson Simone, Jane Cunningham, N. Regina Rabinovitch, Pedro Alonso, Franciso Saute, Pedro Aide and Alfredo Mayor

    Malaria Journal 2017 16:416

    Published on: 16 October 2017

  12. Research

    Malaria prevalence, prevention and treatment seeking practices among nomadic pastoralists in northern Senegal

    Malaria transmission in Senegal is highly stratified, from low in the dry north to moderately high in the moist south. In northern Senegal, along the Senegal River Valley and in the Ferlo semi-desert region, a...

    Mame Cheikh Seck, Julie Thwing, Fatou Ba Fall, Jules Francois Gomis, Awa Deme, Yaye Die Ndiaye, Rachel Daniels, Sarah K. Volkman, Medoune Ndiop, Mady Ba and Daouda Ndiaye

    Malaria Journal 2017 16:413

    Published on: 13 October 2017

  13. Research

    Informing new or improved vector control tools for reducing the malaria burden in Tanzania: a qualitative exploration of perceptions of mosquitoes and methods for their control among the residents of Dar es Salaam

    The effectiveness of malaria prevention with long-lasting insecticidal nets and indoor residual spraying is limited by emerging insecticide resistance, evasive mosquito behaviours that include outdoor biting, ...

    Christina Makungu, Stephania Stephen, Salome Kumburu, Nicodem J. Govella, Stefan Dongus, Zoe Jane-Lara Hildon, Gerry F. Killeen and Caroline Jones

    Malaria Journal 2017 16:410

    Published on: 11 October 2017

  14. Research

    Modelling dynamic change of malaria transmission in holoendemic setting (Dielmo, Senegal) using longitudinal measures of antibody prevalence to Plasmodium falciparum crude schizonts extract

    Evaluation of local Plasmodium falciparum malaria transmission has been investigated previously using the reversible catalytic model based on prevalence of antibody responses to single antigen to estimate serocon...

    Oumy Niass, Philippe Saint-Pierre, Makhtar Niang, Fode Diop, Babacar Diouf, Michel Matar Faye, Fatoumata Diène Sarr, Joseph Faye, Nafissatou Diagne, Cheikh Sokhna, Jean-François Trape, Ronald Perraut, Adama Tall, Abdou Kâ Diongue and Aïssatou Toure Balde

    Malaria Journal 2017 16:409

    Published on: 11 October 2017

  15. Correction

    Correction to: Socioeconomic and demographic characterization of an endemic malaria region in Brazil by multiple correspondence analysis

    After publication of the article [1], it has been brought to our attention that the y-axis of Fig. 6 has been labeled incorrectly. It should read “linear predictor”. This has now been corrected in the original ar...

    Raquel M. Lana, Thais I. S. Riback, Tiago F. M. Lima, Mônica da Silva Nunes, Oswaldo G. Cruz, Francisco G. S. Oliveira, Gilberto G. Moresco, Nildimar A. Honório and Cláudia T. Codeço

    Malaria Journal 2017 16:408

    Published on: 11 October 2017

    The original article was published in Malaria Journal 2017 16:397

  16. Research

    Can the collection of expired long-lasting insecticidal nets reduce their coverage and use? Sociocultural aspects related to LLIN life cycle management and use in four districts in Madagascar

    There is growing awareness of the likely impact increased numbers of LLINs will have on the environment, if not disposed of or recycled appropriately. As part of a World Health Organization (WHO) and United Na...

    Ambinina Ramanantsoa, Marta Wilson-Barthes, Rindra Rahenintsoa, Sarah Hoibak, Harilala Ranaivoharimina, Martha Delphine Rahelimalala, Avotiana Rakotomanga, Alyssa Finlay, Joan Muela Ribera and Koen Peeters Grietens

    Malaria Journal 2017 16:404

    Published on: 10 October 2017

  17. Methodology

    Assessing bed net damage: comparisons of three measurement methods for estimating the size, shape, and distribution of holes on bed nets

    Measuring the physical condition of long-lasting insecticidal nets (LLINs) under field conditions is of great importance for malaria control programmes to guide decisions on how frequently to replace LLINs. Cu...

    Jodi L. Vanden Eng, Don P. Mathanga, Keren Landman, Dyson Mwandama, Anna A. Minta, Monica Shah, James Sutcliffe, Joseph Chisaka, Kim A. Lindblade and Laura Steinhardt

    Malaria Journal 2017 16:405

    Published on: 10 October 2017

  18. Research

    Imported malaria in Spain (2009–2016): results from the +REDIVI Collaborative Network

    Imported malaria is a frequent diagnosis in travellers and migrants. The objective of this study was to describe the epidemiological and clinical characteristics of patients diagnosed with imported malaria wit...

    Francesca F. Norman, Ana López-Polín, Fernando Salvador, Begoña Treviño, Eva Calabuig, Diego Torrús, Antonio Soriano-Arandes, Jose-Manuel Ruíz-Giardín, Begoña Monge-Maillo, Jose-Antonio Pérez-Molina, Ana Perez-Ayala, Magdalena García, Azucena Rodríguez, María Martínez-Serrano, Miren Zubero and Rogelio López-Vélez

    Malaria Journal 2017 16:407

    Published on: 10 October 2017

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