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  1. The evolution of malaria infection has necessitated the development of highly sensitive diagnostic assays, as well as the use of dried blood spots (DBS) as a potential source of deoxyribonucleic acid (DNA) yie...

    Authors: Godfrey Manirakiza, Kennedy Kassaza, Ivan Mugisha Taremwa, Joel Bazira and Fredrick Byarugaba

    Citation: Malaria Journal 2022 21:21

    Content type: Research

    Published on:

  2. Malaria control requires local action. Assessing the vector diversity and abundance provides information on the local malariogenic potential or risk of transmission. This study aimed to determine the Anopheles sp...

    Authors: Nathália Coelho Vargas de Almeida, Jaime Louzada, Maycon Sebastião Alberto Santos Neves, Thiago M. Carvalho, Júlio Castro-Alves, Teresa Fernandes Silva-do-Nascimento, Ananias A. Escalante and Joseli Oliveira-Ferreira

    Citation: Malaria Journal 2022 21:13

    Content type: Research

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  4. Pyrethroid-PBO nets were conditionally recommended for control of malaria transmitted by mosquitoes with oxidase-based pyrethroid-resistance based on epidemiological evidence of additional protective effect wi...

    Authors: Corine Ngufor, Josias Fagbohoun, Abel Agbevo, Hanafy Ismail, Joseph D. Challenger, Thomas S. Churcher and Mark Rowland

    Citation: Malaria Journal 2022 21:20

    Content type: Research

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  5. Vector control tools have contributed significantly to a reduction in malaria burden since 2000, primarily through insecticidal-treated bed nets (ITNs) and indoor residual spraying. In the face of increasing i...

    Authors: Adama Gansané, Baltazar Candrinho, Aimable Mbituyumuremyi, Perpetua Uhomoibhi, Sagnon NFalé, Audu Bala Mohammed, Wamdaogo Moussa Guelbeogo, Antoine Sanou, David Kangoye, Siaka Debe, Moubassira Kagone, Emmanuel Hakizimana, Aline Uwimana, Albert Tuyishime, Chantal M. Ingabire, Joseph H. Singirankabo…

    Citation: Malaria Journal 2022 21:19

    Content type: Methodology

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  6. The capacity of the field staff to conduct activities related to disease surveillance, case management, and vector control has been one of the key components for successfully achieving malaria elimination. Ind...

    Authors: Harsh Rajvanshi, Praveen K. Bharti, Ravendra K. Sharma, Sekh Nisar, Kalyan B. Saha, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur and Altaf A. Lal

    Citation: Malaria Journal 2022 21:18

    Content type: Research

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  7. In South and Central America, Plasmodium malariae/Plasmodium brasilianum, Plasmodium vivax, Plasmodium simium, and Plasmodium falciparum has been reported in New World primates (NWP). Specifically in Costa Rica, ...

    Authors: Andrea Chaves, Gaby Dolz, Carlos N. Ibarra-Cerdeña, Genuar Núñez, Edgar Ortiz-Malavasi E, Sofia Bernal-Valle and Gustavo A. Gutiérrez-Espeleta

    Citation: Malaria Journal 2022 21:17

    Content type: Research

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  8. Vivax malaria is a neglected disease. There is an irrefutable need for better treatments with higher acceptability and efficacy. The treatment efficacy is influenced by many factors, including bioavailability....

    Authors: André Daher, Douglas Pereira Pinto, Laís Bastos da Fonseca, Heliana Martins Pereira, Diego Medeiros Dias da Silva, Letícia de Sá Fernandes Vallim da Silva, Alessandra Lanzillotta Esteves, Juliana J. Soares Medeiros and Jorge Souza Mendonça

    Citation: Malaria Journal 2022 21:16

    Content type: Research

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  9. Early accurate diagnosis and risk assessment for malaria are crucial for improving patients’ terminal prognosis and preventing them from progressing to a severe or critical stage. This study aims to describe t...

    Authors: Gang Li, Donglan Zhang, Zhuo Chen, Da Feng, Xinyan Cai, Xiaoyu Chen, Shangfeng Tang and Zhanchun Feng

    Citation: Malaria Journal 2022 21:11

    Content type: Research

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  10. The eukaryotic parasite Plasmodium falciparum causes millions of malarial infections annually while drug resistance to common anti-malarials is further confounding eradication efforts. Translation is an attractiv...

    Authors: Valentina E. Garcia, Rebekah Dial and Joseph L. DeRisi

    Citation: Malaria Journal 2022 21:15

    Content type: Research

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  11. Malaria incidence has declined in Ethiopia in the past 10 years. Current malaria diagnostic tests, including light microscopy and rapid antigen-detecting diagnostic tests (RDTs) cannot reliably detect low-dens...

    Authors: Mahlet Belachew, Mistire Wolde, Desalegn Nega, Bokretsion Gidey, Legessie Negash, Ashenafi Assefa, Geremew Tasew, Adugna Woyessa and Adugna Abera

    Citation: Malaria Journal 2022 21:9

    Content type: Research

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  12. The order Accipitriformes comprises the largest group of birds of prey with 260 species in four families. So far, 21 haemosporidian parasite species have been described from or reported to occur in accipitrifo...

    Authors: Josef Harl, Tanja Himmel, Gediminas Valkiūnas, Mikas Ilgūnas, Nora Nedorost, Julia Matt, Anna Kübber-Heiss, Amer Alic, Cornelia Konicek and Herbert Weissenböck

    Citation: Malaria Journal 2022 21:14

    Content type: Research

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  13. Despite significant decline in malarial incidence and mortality in countries across the Greater Mekong Subregion, the disease remains a public health challenge in the region; transmission continues mainly amon...

    Authors: Monnaphat Jongdeepaisal, Soulixay Inthasone, Panarasri Khonputsa, Vilayvone Malaphone, Kulchada Pongsoipetch, Tiengkham Pongvongsa, Mayfong Mayxay, Keobouphaphone Chindavongsa, Christopher Pell and Richard J. Maude

    Citation: Malaria Journal 2022 21:8

    Content type: Research

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  14. A malaria control programme based on distribution of long-lasting insecticidal bed nets (LLINs) and artemisinin combination therapy began in Papua New Guinea in 2009. After implementation of the programme, sub...

    Authors: John B. Keven, Michelle Katusele, Rebecca Vinit, Daniela Rodríguez-Rodríguez, Manuel W. Hetzel, Leanne J. Robinson, Moses Laman, Stephan Karl and Edward D. Walker

    Citation: Malaria Journal 2022 21:7

    Content type: Research

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  15. The use of data in targeting malaria control efforts is essential for optimal use of resources. This work provides a practical mechanism for prioritizing geographic areas for insecticide-treated net (ITN) dist...

    Authors: Alyssa J. Young, Will Eaton, Matt Worges, Honelgn Hiruy, Kolawole Maxwell, Bala Mohammed Audu, Madeleine Marasciulo, Charles Nelson, James Tibenderana and Tarekegn A. Abeku

    Citation: Malaria Journal 2022 21:10

    Content type: Research

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  16. The GMZ2.6c malaria vaccine candidate is a multi-stage Plasmodium falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C protein genetically fused to GMZ2, a fusion protein of GLURP...

    Authors: Barbara Oliveira Baptista, Ana Beatriz Lopes de Souza, Evelyn Kety Pratt Riccio, Cesare Bianco-Junior, Paulo Renato Rivas Totino, João Hermínio Martins da Silva, Michael Theisen, Susheel Kumar Singh, Linda Eva Amoah, Marcelo Ribeiro-Alves, Rodrigo Medeiros Souza, Josué Costa Lima-Junior, Cláudio Tadeu Daniel-Ribeiro and Lilian Rose Pratt-Riccio

    Citation: Malaria Journal 2022 21:6

    Content type: Research

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  17. Long-lasting insecticidal nets (LLINs) are the main vector control tool for pregnant women, but their efficacy may be compromised, in part, due to pyrethroid resistance. In 2017, the Ugandan Ministry of Health...

    Authors: Michelle E. Roh, Brenda Oundo, Grant Dorsey, Stephen Shiboski, Roly Gosling, M. Maria Glymour, Sarah G. Staedke, Adam Bennett, Hugh Sturrock and Arthur Mpimbaza

    Citation: Malaria Journal 2022 21:5

    Content type: Research

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  18. The efficacies of artemisinin based combinations have been excellent in Africa, but also comprehensive evidence regarding their safety would be important. The aim of this review was to synthesize available evi...

    Authors: Dawit Getachew Assefa, Eden Dagnachew Zeleke, Wondwosen Molla, Nebiyu Mengistu, Ahmedin Sefa, Andualem Mebratu, Asresu Feleke Bate, Etaferaw Bekele, Gizachew Yesmaw and Eyasu Makonnen

    Citation: Malaria Journal 2022 21:4

    Content type: Research

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  20. Genotyping of the three Plasmodium falciparum polymorphic genes, msp1, msp2 and glurp, has been adopted as a standard strategy to distinguish recrudescence from new infection in drug efficacy clinical trials. How...

    Authors: Wahib M. Atroosh, Yee-Ling Lau, Georges Snounou, Meram Azzani and Hesham M. Al-Mekhlafi

    Citation: Malaria Journal 2022 21:2

    Content type: Research

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  22. Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge of the disease progression and resilien...

    Authors: Mariko S. Peterson, Chester J. Joyner, Jessica A. Brady, Jennifer S. Wood, Monica Cabrera-Mora, Celia L. Saney, Luis L. Fonseca, Wayne T. Cheng, Jianlin Jiang, Stacey A. Lapp, Stephanie R. Soderberg, Mustafa V. Nural, Jay C. Humphrey, Allison Hankus, Deepa Machiah, Ebru Karpuzoglu…

    Citation: Malaria Journal 2021 20:486

    Content type: Research

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  23. Over the past two decades, Zanzibar substantially reduced malaria burden. As malaria decreases, sustainable improvements in control interventions may increasingly depend on accurate knowledge of malaria risk f...

    Authors: Humphrey R. Mkali, Erik J. Reaves, Shabbir M. Lalji, Abdul-Wahid Al-mafazy, Joseph J. Joseph, Abdullah S. Ali, Faiza B. Abbas, Mohamed H. Ali, Wahida S. Hassan, Chonge Kitojo, Naomi Serbantez, Bilali I. Kabula, Ssanyu S. Nyinondi, Donal Bisanzio, Mike McKay, Erin Eckert…

    Citation: Malaria Journal 2021 20:485

    Content type: Research

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  24. In Uganda, artemether-lumefantrine (AL) is first-line therapy and dihydroartemisinin-piperaquine (DP) second-line therapy for the treatment of uncomplicated malaria. This study evaluated the efficacy and safet...

    Authors: Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Samuel Gonahasa, Victor Asua, Sam Gudoi, Ruth Kigozi, James Tibenderana, John Bosco Bwanika, Agaba Bosco, Denis Rubahika, Daniel Kyabayinze, Jimmy Opigo, Damian Rutazana…

    Citation: Malaria Journal 2021 20:484

    Content type: Research

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  25. Ethiopia is one of the few countries in Africa where Plasmodium vivax commonly co-exists with Plasmodium falciparum, and which accounts for ~ 40% of the total number of malaria infections in the country. Regardle...

    Authors: Tsige Ketema, Ketema Bacha, Kefelegn Getahun and Quique Bassat

    Citation: Malaria Journal 2021 20:483

    Content type: Research

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  26. Information on the foci of Plasmodium species infections is essential for any country heading towards elimination. Odisha, one of the malaria-endemic states of India is targeting elimination of malaria by 2030. T...

    Authors: Madhusmita Bal, Ramakanta Rana, Arundhuti Das, Hemant Kumar Khuntia, Nilam Somalkar, Niranjan Sahoo, Jyoti Ghosal, Sanghamitra Pati, Ambarish Dutta and Manoranjan Ranjit

    Citation: Malaria Journal 2021 20:482

    Content type: Research

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  27. Malaria causes more than 200 million cases of illness and 400,000 deaths each year across 90 countries. The World Health Organization (WHO) set a goal for 35 countries to eliminate malaria by 2030, with an int...

    Authors: Kim A. Lindblade, Hong Li Xiao, Amanda Tiffany, Gawrie Galappaththy and Pedro Alonso

    Citation: Malaria Journal 2021 20:481

    Content type: Research

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  28. Existing mechanisms of insecticide resistance are known to help the survival of mosquitoes following contact with chemical compounds, even though they could negatively affect the life-history traits of resista...

    Authors: Adandé A. Medjigbodo, Luc S. Djogbénou, Oswald Y. Djihinto, Romaric B. Akoton, Emmanuella Abbey, Rosaria M. Kakossou, Eric G. Sonounameto, Esther B. J. Salavi, Laurette Djossou and Athanase Badolo

    Citation: Malaria Journal 2021 20:480

    Content type: Research

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  29. Plasmodium vivax blood-stage relapses originating from re-activating hypnozoites are a major barrier for control and elimination of this disease. Radical cure is a form of therapy capable of addressing this probl...

    Authors: John H. Huber, Cristian Koepfli, Guido España, Narimane Nekkab, Michael T. White and T. Alex Perkins

    Citation: Malaria Journal 2021 20:479

    Content type: Research

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  30. The novel anti-malarial cipargamin (KAE609) has potent, rapid activity against Plasmodium falciparum. Transient asymptomatic liver function test elevations were previously observed in cipargamin-treated subjects ...

    Authors: Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P. Grobusch, Etienne Karita, Henry Mugerwa, Stephen Asiimwe, Abraham Oduro, Bakary Fofana, Seydou Doumbia, Jay Prakash Jain, Sarita Barsainya, Gerd A. Kullak-Ublick, Guoqin Su, Esther K. Schmitt, Katalin Csermak…

    Citation: Malaria Journal 2021 20:478

    Content type: Research

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  31. Countries in the Greater Mekong sub-region (GMS) aim to eliminate all forms of malaria by 2030. In Cambodia and Vietnam, forest-goers are at an increased risk of malaria. Universal access to prompt diagnosis a...

    Authors: Mahesh Paudel, Kemi Tesfazghi, Hoa Nguyen, Sochea Phok, Shwetha Srinivasan and Jennifer Wheeler

    Citation: Malaria Journal 2021 20:477

    Content type: Research

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  32. Efforts to improve the impact of long-lasting insecticidal nets (LLINs) should be informed by understanding of the causes of decay in effect. Holes in LLINs have been estimated to account for 7–11% of loss in ...

    Authors: Thomas Smith, Adrian Denz, Maurice Ombok, Nabie Bayoh, Hannah Koenker, Nakul Chitnis, Olivier Briet, Joshua Yukich and John E. Gimnig

    Citation: Malaria Journal 2021 20:476

    Content type: Research

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  33. In March 2020, the government of Uganda implemented a strict lockdown policy in response to the COVID-19 pandemic. Interrupted time series analysis (ITSA) was performed to assess whether major changes in outpa...

    Authors: Jane F. Namuganga, Jessica Briggs, Michelle E. Roh, Jaffer Okiring, Yasin Kisambira, Asadu Sserwanga, James A. Kapisi, Emmanuel Arinaitwe, Chris Ebong, Isaac Ssewanyana, Catherine Maiteki-Ssebuguzi, Moses R. Kamya, Sarah G. Staedke, Grant Dorsey and Joaniter I. Nankabirwa

    Citation: Malaria Journal 2021 20:475

    Content type: Research

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  34. Development of an effective vaccine against blood-stage malaria requires the induction of long-term immune responses. Plasmodium vivax Reticulocyte Binding Protein 1a (PvRBP1a) is a blood-stage parasite antigen w...

    Authors: Piyawan Kochayoo, Pattarawan Sanguansuttikul, Pongsakorn Thawornpan, Kittikorn Wangriatisak, John H. Adams, Francis B. Ntumngia and Patchanee Chootong

    Citation: Malaria Journal 2021 20:474

    Content type: Research

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  35. Malaria, acute respiratory infections (ARIs) and diarrhoea are the leading causes of morbidity and mortality among children under 5 years old. Estimates of the malaria incidence are available from a previous s...

    Authors: Tinashe A. Tizifa, Alinune N. Kabaghe, Robert S. McCann, William Nkhono, Spencer Mtengula, Willem Takken, Kamija S. Phiri and Michele van Vugt

    Citation: Malaria Journal 2021 20:473

    Content type: Research

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  36. The gold standard for diagnosing Plasmodium falciparum infection is microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of this procedure for infection surveillance and malaria co...

    Authors: Kevin O. Ochwedo, Collince J. Omondi, Edwin O. Magomere, Julius O. Olumeh, Isaiah Debrah, Shirley A. Onyango, Pauline W. Orondo, Benyl M. Ondeto, Harrysone E. Atieli, Sidney O. Ogolla, John Githure, Antony C. A. Otieno, Andrew K. Githeko, James W. Kazura, Wolfgang R. Mukabana and Yan Guiyan

    Citation: Malaria Journal 2021 20:472

    Content type: Research

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  37. Model-based geostatistical (MBG) methods have been extensively used to map malaria risk using community survey data in low-resource settings where disease registries are incomplete or non-existent. However, th...

    Authors: Emanuele Giorgi, Peter M. Macharia, Jack Woodmansey, Robert W. Snow and Barry Rowlingson

    Citation: Malaria Journal 2021 20:471

    Content type: Research

    Published on:

  38. Malaria-associated anaemia, arising from symptomatic, asymptomatic and submicroscopic infections, is a significant cause of morbidity worldwide. Induced blood stage malaria volunteer infection studies (IBSM-VI...

    Authors: Stephen D. Woolley, Louise Marquart, John Woodford, Stephan Chalon, Joerg J. Moehrle, James S. McCarthy and Bridget E. Barber

    Citation: Malaria Journal 2021 20:470

    Content type: Research

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  39. Anopheles arabiensis is a member of Anopheles gambiae complex and the main malaria vector in Sudan. There is insufficient population genetics data available on An. arabiensis for an understanding of vector popula...

    Authors: Mashair Sir El Khatim Mustafa, Zairi Jaal, Sumia Abu Kashawa and Siti Azizah Mohd Nor

    Citation: Malaria Journal 2021 20:469

    Content type: Research

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  40. In Ethiopia, despite improvements in coverage and access, utilization of long-lasting insecticidal nets (LLINs) remains a challenge. Different household-level factors have been identified as associated with LL...

    Authors: Honelgn Nahusenay Hiruy, Ayele Zewde, Seth R. Irish, Semira Abdelmenan, Adugna Woyessa, Yonas Wuletaw, Hiwot Solomon, Mebrahtom Haile, Achamyelesh Sisay, Sheleme Chibsa, Alemayehu Worku, Josh Yukich, Yemane Berhane and Joseph Keating

    Citation: Malaria Journal 2021 20:468

    Content type: Research

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  41. With effective vector control and case management, substantial progress has been made towards eliminating malaria on the islands of São Tomé and Príncipe (STP). This study assessed the dynamic changes in the g...

    Authors: Ying-An Chen, Tsen-Ju Shiu, Lien-Fen Tseng, Chien-Fu Cheng, Wei-Liang Shih, Arlindo Vicente de Assunção Carvalho and Kun-Hsien Tsai

    Citation: Malaria Journal 2021 20:467

    Content type: Research

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  43. Central America and the island of Hispaniola have set out to eliminate malaria by 2030. However, since 2014 a notable upturn in the number of cases has been reported in the Mosquitia region shared by Nicaragua...

    Authors: Gustavo Fontecha, Alejandra Pinto, Osman Archaga, Sergio Betancourth, Lenin Escober, Jessica Henríquez, Hugo O. Valdivia, Alberto Montoya and Rosa Elena Mejía

    Citation: Malaria Journal 2021 20:465

    Content type: Research

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  44. Malaria vector control in the Democratic Republic of the Congo is plagued by several major challenges, including inadequate infrastructure, lack of access to health care systems and preventative measures, and ...

    Authors: Janvier Bandibabone, Charles McLoughlin, Sévérin N’Do, Chimanuka Bantuzeko, Vital Byabushi, Muhigwa Jeanberckmans, Maite Guardiola, Bertin Zawadi, Abdoulaye Diabaté, Jorian Prudhomme, Thomas Walker and Louisa A. Messenger

    Citation: Malaria Journal 2021 20:464

    Content type: Research

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  45. Malaria is one of the deadliest diseases in the world, particularly in Africa. As such, resistance to anti-malarial drugs is one of the most important problems in terms of global malaria control. This study as...

    Authors: Pedro Berzosa, Irene Molina de la Fuente, Thuy-Huong Ta-Tang, Vicenta González, Luz García, Ana Rodríguez-Galet, Ramón Díaz-Regañón, Rosario Galán, Laura Cerrada-Gálvez, Policarpo Ncogo, Matilde Riloha and Agustin Benito

    Citation: Malaria Journal 2021 20:463

    Content type: Research

    Published on:

  47. Molecular diagnostic tools have been incorporated in insecticide resistance monitoring programmes to identify underlying genetic basis of resistance and develop early warning systems of vector control failure....

    Authors: Sharon Mwagira-Maina, Steven Runo, Lucy Wachira, Stanley Kitur, Sarah Nyasende, Brigid Kemei, Eric Ochomo, Damaris Matoke-Muhia, Charles Mbogo and Luna Kamau

    Citation: Malaria Journal 2021 20:461

    Content type: Research

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  48. A detailed analysis of household and individual level Plasmodium infection patterns in two low-endemic districts of Meghalaya was undertaken to better understand the epidemiology of malaria in northeast India.

    Authors: Rajiv Sarkar, Anne Kessler, Bandapkupar Mawkhlieng, Steven A. Sullivan, Mark L. Wilson, Jane M. Carlton and Sandra Albert

    Citation: Malaria Journal 2021 20:460

    Content type: Research

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  49. Use of long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), community-based malaria education, prompt diagnosis and treatment are key programme components of malaria prevention and control i...

    Authors: Abebe Asale, Zewdu Abro, Bayu Enchalew, Alayu Teshager, Aklilu Belay, Menale Kassie and Clifford Maina Mutero

    Citation: Malaria Journal 2021 20:459

    Content type: Research

    Published on:

  50. In April 2017, the Thai Ministry of Public Health (MoPH) was alerted to a potential malaria outbreak among civilians and military personnel in Sisaket Province, a highly forested area bordering Cambodia. The o...

    Authors: Michelle E. Roh, Kanyarat Lausatianragit, Nithinart Chaitaveep, Krisada Jongsakul, Prayuth Sudathip, Chatree Raseebut, Sutchana Tabprasit, Prasert Nonkaew, Michele Spring, Montri Arsanok, Parat Boonyarangka, Sabaithip Sriwichai, Piyaporn Sai-ngam, Chaiyaporn Chaisatit, Peerapol Pokpong, Preecha Prempree…

    Citation: Malaria Journal 2021 20:458

    Content type: Research

    Published on:

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