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Convalescent Plasmodium falciparum-specific seroreactivity does not correlate with paediatric malaria severity or Plasmodium antigen exposure

Antibody to Plasmodium falciparum antigens is essential for protection from symptomatic malaria.  Protein microarrays provide a high throughput platform for screening small volumes of sample for seroreactivity. Plasma from acute infection and convalescence in children with uncomplicated and cerebral malaria was compared using a 1000 feature array. Despite differences in parasite burden and PfEMP1 exposure, children with uncomplicated and cerebral malaria have similar breadth and magnitude of P. falciparum and PfEMP1 seroreactivity. Conserved PfEMP1 domains are more prominent targets of cross-reactive antibodies than variable domains in children with symptomatic malaria. Thus, protein microarrays have utility in identifying cross-reactive Plasmodium antigens.

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Congratulations to the BSP Spring Meeting 2018 Poster Prize winners!

Malaria Journal is proud to announce the winners of the Spring Meeting poster prize competition at the British Society of Parasitology. Congrats to you all!


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Thematic series
Time to go for vivax
Edited by: Marcus V Lacerda and Hernando A del Portillo


Thematic series
ACT now: anti-malarial market complexity one decade after the introduction of artemisinin combination therapy – evidence from sub-Saharan Africa and the Greater Mekong Sub-region

Thematic series

Ivermectin to reduce malaria transmission


Thematic series
Housing and malaria
Edited by: Dr. Lucy Tusting, Dr. Jo Lines and Barbary Willey


Thematic series
Re-imagining malaria – a platform for reflections to widen horizons in malaria control
Edited by: Dr. Julian Eckl, Dr. Susanna Hausmann Muela

Cross journal collection
Every day is Malaria Day


Cross journal collection
Reviewer acknowledgements 2013


Thematic series
WHO global malaria recommendations 2012 - 2015


Thematic series
The ACTwatch project: monitoring anti-malarial markets in seven countries

Thematic series
Travellers' malaria
Edited by: Prof Patricia Schlagenhauf


Thematic series
National malaria control programme (NMCP) Best Practice Sharing
Edited by: Prof Robert William Snow

Thematic series
Towards malaria elimination


Thematic series
The world antimalarial resistance network (WARN)

Aims and Scope

Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialties involved in this very broad discipline, from the bench to the bedside and to the field. Malaria Journal offers a fast publication schedule while maintaining rigorous peer-review; this is achieved by managing the whole of the publication process electronically, from submission to peer-review.

Editor-in-Chief - Marcel Hommel, University of Liverpool, UK

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Time to go for Vivax

In 2002, the vivax malaria community created a forum for providing a friendly environment to share and discuss research results on Plasmodium vivax. Meetings were held in Bangkok, Rockville, Panama, Barcelona, Bali, and this year, in Manaus.

The aim of this Thematic series, ‘Time to go for vivax’ (the motto of the Manaus meeting) is to emphasize this biennial event and the role it plays in promoting the study of Plasmodium vivax. The articles in the series are all based on presentations given in Manaus.

Guest editors: Marcus V Lacerda and Hernando A del Portillo

ACT now: anti-malarial market complexity one decade after the introduction of artemisinin combination therapy – evidence from sub-Saharan Africa and the Greater Mekong Sub-region

ACTwatch report on their 10-year monitoring of ACT usage in sub-Saharan Africa and in the Greater Mekong sub- region, make recommendations and share their data with the malaria community. They have spoken to BugBitten about their work and their motivation for making their datasets publicly available.

Ivermectin to reduce malaria transmission

Ivermectin has been used to treat some NTDs for years, but its potential use to block malaria transmission is not well known. Carlos Chaccour and colleagues review the role the ivermectin can play in reducing malaria. Carlos Chaccour and Regina Rabinovich also discuss the series and ivermectin in their interview with BugBitten blog.



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