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Table 2 List of Important differentially expressed probes after administration of SP in murine Liver.

From: A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine

Spot labels

Fold Change

Gene Name/Description

GO : Biological function

5638

2.01

Histone deacetylase 9

Histone deacetylase activity

728

2.04

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

ATP binding

15419

2.33

DEAH (Asp-Glu-Ala-His) box polypeptide 15

ATP-dependent helicase activity

1745

2.66

Transketolase

Calcium ion binding

14698

2.76

Procollagen, type VI, alpha 2

Cell adhesion

17252

2.02

Procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

Endopeptidase inhibitor activity

2107

2.62

Lymphocyte antigen 6 complex, locus G6C

Extracellular space

14620

2.11

RNA binding motif protein, X chromosome retrogene

RNA binding

21645

2.11

RNA binding motif protein 28

RNA binding

12990

2.11

Eukaryotic translation initiation factor 1

Translation factor activity

21844

-3.44

CDC42 effector protein (Rho GTPase binding) 1

Signal transduction

8922

-2.20

Serine (or cysteine) peptidase inhibitor, clade B, member 6a

Endopeptidase inhibitor activity

5874

-7.13

Cytochrome c oxidase subunit VIb polypeptide 2

Unknown

6344

-5.56

Tumor protein D52

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11499

-2.21

Unknown

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11550

-2.54

RIKEN cDNA 4930471M23 gene

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11891

-2.26

TBC1 domain family, member 19

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  1. Fold change (FC) >2(Up regulated) and FC<-2 (Down regulated) and P < 0.01.