From: High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children
dhfr
N = 106
%
Single mutant
1
Double mutant
2
Triple mutant
98
92
MIX
5
dhps
N = 121
Sensitive
Single mutant (436A only)
18
15
Single mutant (437G only)
60
50
Double mutant (436A + 437G)
6
Double mutant (437G + 540E)
4
3
31
26