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Table 2 Prevalence of dhfr and dhps haplotypes in isolates from Plasmodium falciparum positive patients from Lambaréné, Gabon, 2005-2007

From: High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children

dhfr

N = 106

%

Single mutant

1

1

Double mutant

2

2

Triple mutant

98

92

MIX

5

5

dhps

N = 121

%

Sensitive

2

2

Single mutant (436A only)

18

15

Single mutant (437G only)

60

50

Double mutant (436A + 437G)

6

5

Double mutant (437G + 540E)

4

3

MIX

31

26

  1. MIX: infections with mixed strains