Table 5 Prevalence of dhps gene mutations at enrolment and at day of failure in children included in the in vivo study
DHPS | |||||
|---|---|---|---|---|---|
Pre-treatment | |||||
436/437 SA | 436/437 SG | 436/437 AA | 436/437 AG | N = 29 | % |
0 | 1 | 0 | 0 | 11 | 38 |
1 | 0 | 0 | 0 | 1 | 3 |
1 | 1 | 0 | 0 | 1 | 3 |
0 | 1 | 0 | 1 | 2 | 7 |
0 | 0 | 1 | 0 | 2 | 7 |
0 | 1 | 1 | 0 | 7 | 24 |
1 | 0 | 1 | 0 | 1 | 3 |
0 | 1 | 1 | 1 | 4 | 14 |
Post-treatment | |||||
436/437 SA | 436/437 SG | 436/437 AA | 436/437 AG | N = 26 | % |
0 | 0 | 0 | 0 | 11 | 42 |
0 | 1 | 0 | 0 | 10 | 38 |
1 | 1 | 0 | 0 | 1 | 4 |
0 | 0 | 0 | 1 | 1 | 4 |
0 | 0 | 1 | 0 | 2 | 8 |
0 | 1 | 1 | 0 | 1 | 4 |