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Table 2 Sensitivity and specificity of RDTs in the longitudinal study and CSS in Korogwe and Muheza districts

From: Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

  

Positive rate

  

Study type

Category (n)

Microscopy

(%, 95% CI)

RDTs

(%, 95% CI)

Sensitivity

(%, 95% CI)

Specificity

(%, 95% CI)

Longitudinal study

Under-fives + fever (n = 2116)

27.8 (25.9-29.7)

31.9(29.9-33.9)

92.1(89.9-94.3)

91.3(89.9-92.7)

 

Under-fives, no fever(n = 2159)

12.1(10.7-13.5)

14.3(12.8-15.8)

85.4(81.1-89.7)

95.6(94.7-96.5)

 

Above 5 years + fever (n = 3750)

37.3(36.0-39.0)

48.6(47.0-50.2)

92.3(90.9-93.1)

77.5(75.8-79.8)

 

Above 5 years, no fever (n = 10186)

15.0(14.3-15.7)

22.1(21.3-22.9)

84.6(82.8-86.4)

89.0(88.2-89.6)

 

Overall (18213)

20.8(20.2-21.4)

27.8(27.1-28.5)

88.6(87.5-89.7)

88.2(87.7-88.7)

CSS

Under-fives + fever (n = 83)

32.5(22.4-42.6)

41.0(30.4-51.6)

96.3(89.0-100.0)

85.7(76.5-94.9)

 

Under-fives, no fever(n = 1940)

8.0(6.8-9.2)

10.5(9.1-11.9)

66.7(59.3-74.1)

94.4(93.3-95.5)

 

Above 5 years + fever (n = 96)

40.9(31.1-50.7)

41.9(32.0-51.8)

89.5(79.8-99.2)

90.9(83.3-98.5)

 

Above 5 years, no fever (n = 3906)

22.6(21.3-23.9)

18.0(16.8-19.2)

60.5(57.1-63.9)

94.5(93.7-95.3)

 

Overall (n = 5759)

18.2(17.2-19.2)

16.2(15.2-17.2)

63.4(59.8-67.1)

94.3(93.6-95.0)

  1. CSS = Cross-sectional surveys, RDT = malaria rapid diagnostic tests, % = percentage,°C = degree centigrade, 95% CI = 95% confidence interval