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Table 5 Fisher's exact test of association between polymorphisms and in vitro drug response, N = 31

From: Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro

Polymorphism vs. drug p value
pfcrt (K76T) vs. chloroquine 0.001
pfATPase6 (D639G) vs. artesunate 0.423
pfcrt (K76T) vs. artesunate 1.000
pfmdr1 (N86Y) vs. artesunate 1.000
pfmdr1 (Y184F) vs. artesunate 1.000
pfmdr1 (N86Y) vs. chloroquine 1.000
pfmdr1 (Y184F) vs. chloroquine 0.104
pfmdr1 (N86Y) vs. amodiaquine 1.000
pfmdr1 (Y184F) vs. amodiaquine 0.253
pfmdr1 (N86Y) vs. quinine 1.000
pfmdr1 (Y184F) vs. quinine 1.000
pfmdr1 (double mutant) vs. artesunate 0.577
pfmdr1 (double mutant) vs. chloroquine 1.000
pfmdr1 (double mutant) vs. amodiaquine 0.630
pfmdr1 (double mutant) vs. quinine 1.000