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Table 4 Evolution of biological parameters in the two groups

From: Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

 

DP

AL

 

D1

D4

D1-D4

p*

D1

D4

D1-D4

p*

AST (IU/l)

(SD)

26.48

(15.17)

24.79

(12.10)

1.70

(17.51)

0.190

29.62

(26.14)

38.24

(131.0)

- 8.63

(132.6)

0.389

ALT (IU/l)

(SD)

18.91

(12.71)

19.73

(12.91)

- 0.82

(13.77)

0.418

24.20

(37.46)

34.19

(138.47)

- 9.99

(140.5)

0.347

Creatinin (mg/l)

(SD)

6.81

(2.46)

6.70

(2.41)

0.11

(1.52)

0.317

6.86

(2.45)

6.51

(2.51)

0.35

(1.9)

0.001

Bilirubin (mg/l)

(SD)

10.49

(7.39)

6.31

(2.99)

4.18

(7.42)

< 0.001

11.19

(8.51)

6.27

(3.30)

4.92

(8.57)

< 0.001

Haemoglobin (g/dl)

(SD)

10.80

(2.07)

10.66

(2.18)

0.14

(1.56)

0.221

10.75

(2.07)

10.39

(2.08)

0.36

(1.48)

0.001

  1. *paired t test
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Malaria Journal

ISSN: 1475-2875

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