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Table 4 Evolution of biological parameters in the two groups

From: Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

  DP AL
  D1 D4 D1-D4 p* D1 D4 D1-D4 p*
AST (IU/l) (SD) 26.48 (15.17) 24.79 (12.10) 1.70 (17.51) 0.190 29.62 (26.14) 38.24 (131.0) - 8.63 (132.6) 0.389
ALT (IU/l) (SD) 18.91 (12.71) 19.73 (12.91) - 0.82 (13.77) 0.418 24.20 (37.46) 34.19 (138.47) - 9.99 (140.5) 0.347
Creatinin (mg/l) (SD) 6.81 (2.46) 6.70 (2.41) 0.11 (1.52) 0.317 6.86 (2.45) 6.51 (2.51) 0.35 (1.9) 0.001
Bilirubin (mg/l) (SD) 10.49 (7.39) 6.31 (2.99) 4.18 (7.42) < 0.001 11.19 (8.51) 6.27 (3.30) 4.92 (8.57) < 0.001
Haemoglobin (g/dl) (SD) 10.80 (2.07) 10.66 (2.18) 0.14 (1.56) 0.221 10.75 (2.07) 10.39 (2.08) 0.36 (1.48) 0.001
  1. *paired t test