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Table 4 Anti-relapse efficacy of tafenoquine in various regimens and primaquine in human cases compared to chloroquine in Thailand (from Walsh et al 1999; 2004).

From: Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)

Drug Dose Total Dose #Subjects #Relapses Efficacy (% +/- 95% CI) Comment on Relapse
Tafenoquine 500 mg 500 9 1 87 (-37-100) Relapse delayed
Tafenoquine 600 mg 600 18 1 96 (67-99) Vomiting
Tafenoquine 600 mg × 3 1800 19 0 100 (78-100)  
Tafenoquine 300 mg × 7 2100 19 0 100 (78-100)  
Tafenoquine 300 mg × 7 2100 15 0 100 (24-100)  
Tafenoquine 500 mg × 3, repeated 3000 11 1 87 (-34-100) Relapse delayed
Primaquine 15 mg × 14   12 3 80 (15-97)