Table 1 Prevalence of mutations conferring resistance to SP in P. falciparum isolates from Angola.
From: Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola
Prevalence of mutations in pfdhfr and pfdhps genes (%) | ||||||
|---|---|---|---|---|---|---|
pfdhfr | pfdhps | |||||
Province | 51 | 59 | 108 | 437 | 540 | |
Alleles | n (%) | n (%) | n (%) | n (%) | n (%) | |
wild type | 0 (0) | 16 (27,6) | 0 (0) | 8 (12,1) | 55 (83,3) | |
Cabinda | mutant | 70 (98,6) | 28 (48,3) | 64 (100) | 57 (86,4) | 3 (4,5) |
mix infection | 1 (1,4) | 14 (24,1) | 0 (0) | 1 (1,5) | 8 (12,1) | |
wild type | 1(1,85) | 19 (35,8) | 0(0) | 0 (0) | 53 (98,1) | |
Uige | mutant | 52 (96,3) | 15 (28,3) | 50 (100) | 52 (96,3) | 1 (1,9) |
mix infection | 1 (1,85) | 19 (35,8) | 0 (0) | 2 (3,7) | 0 (0) | |
wild type | 2 (2,1) | 46 (49,5) | 0 (0) | 0 (0) | 92 (95,8) | |
Kwanza Norte | mutant | 91 (94,8) | 25 (26,9) | 92 (100) | 93 (96,9) | 2 (2,1) |
mix infection | 3 (3,1) | 22 (23,7) | 0 (0) | 3 (3,1) | 2 (2,1) | |
wild type | 7 (3,4) | 127 (62,6) | 3 (1,5) | 16 (7,7) | 189 (90,9) | |
Malanje | mutant | 173 (83,2) | 12 (5,9) | 199 (98) | 156 (75) | 5 (2,4) |
mix infection | 28 (13,5) | 64 (31,5) | 1 (0,5) | 34 (16,3) | 13 (6,3) | |
wild type | 0 (0) | 5 (45,5) | 0 (0) | 2 (12,5) | 11 (61,1) | |
Huambo | mutant | 22 (95,7) | 3 (27,3) | 21 (100) | 6 (37,5) | 1 (5,6) |
mix infection | 1 (4,4) | 3 (27,3) | 0 (0) | 8 (50) | 6 (33,3) | |
wild type | 10 (2,2) | 213 (51,0) | 3 (0,7) | 26 (5,9) | 390 (87,1) | |
Total | mutant | 408 (90,3) | 83 (19,9) | 426 (99,1) | 364 (83,1) | 29 (6,5) |
mix infection | 34 (7,5) | 122 (29,2) | 1 (0,2) | 48 (11,0) | 29 (6,5) | |