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Table 7 Summary of changes in total bilirubin and alanine aminotransferase during the first episode

From: Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial

  ASAQ AL p-value
Total bilirubin mg/dL)    
   Day 0 (n = 184) (n = 182)  
Mean ± SD 1.46 ± 0.99 1.50 ± 1.51 0.796
Range 0.02-5.52 0.01-17.27  
   Day 7 (n = 182) (n = 180)  
Mean ± SD 0.83 ± 1.45 0.80 ± 1.04 0.825
Range 0.03-19.25 0.04-13.18  
   Day 28 (n = 181) (n = 175)  
Mean ± SD 0.60 ± 0.35 0.80 ± 1.04 1.000
Range 0.01-2.33 0.03-2.57  
ALT (UI/L)    
   Day 0 (n = 184) (n = 182)  
Mean ± SD 29.2 ± 30.0 27.8 ± 29.8 0.505
Range 2-199 1-217  
   Day 7 (n = 183) (n = 181)  
Mean ± SD 22.4 ± 15.7 25.1 ± 27.4 0.877
Range 1-95 1-218  
   Day 28 (n = 181) (n = 175)  
Mean ± SD 20.9 ± 14.9 19.5 ± 15.9 0.053
Range 1-110 3-99