Table 2 Prevalence of in vitro resistant Plasmodium falciparum isolates from Dakar or with reduced susceptibility to chloroquine (CQ), monodesethylamodiaquine (MDAQ), lumefantrine (LMF), dihydroartemisinin (DHA), quinine (QN), mefloquine (MQ) and doxycycline (DOX)
Drug | Resistant or reduced susceptible isolate IC50 | Resistant or reduced susceptible Ratio (isolate IC50 /3D7 IC50) | ||||
|---|---|---|---|---|---|---|
| Â | Cut-off | No | % | Cut-off | No | % |
CQ | 77 nM | 18/83 | 22 | 5 | 18/83 | 22 |
MDAQ | 61 nM | 5/83 | 6 | 3 | 5/83 | 6 |
LMF | 115 nM | 3/79 | 4 | 5 | 1/79 | 1 |
DHA | 12 nM | 0/88 | 0 | 7 | 1/88 | 1 |
QN | 611 nM | 9/82 | 11 | 5 | 5/82 | 6 |
MQ | 30 nM | 48/88 | 55 | 0.6 | 44/88 | 50 |
DOX | 37 μM | 6/76 | 8 | 3 | 9/76 | 12 |