Figure 2

LD plot and haplotype frequency in Thai malaria patients. A, LD plot among six SNPs analysed in 708 Thai malaria patients. A pairwise r² value is shown in each square. Darker shading indicates higher r² value. B, Haplotype frequencies in mild and cerebral malaria patients. Only haplotypes with frequency of more than 0.02 either in mild or in cerebral malaria patients are shown. Permutation P-values were calculated for single SNPs and haplotypes from 100,000 permutations.